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A formylation reaction in organic chemistry is the catch-all name for any organic reaction in which an organic compound is functionalized with a formyl group (-CH=O).
Aromatic formylation reactions via electrophilic aromatic substitution include:
- Dimethylformamide and phosphorus oxychloride in the Vilsmeier-Haack reaction
- Hexamine in the Duff reaction and the Sommelet reaction
- Carbon monoxide and hydrochloric acid in the Gattermann-Koch reaction
- Zinc cyanide and hydrochloric acid in the Gatterman aldehyde synthesis
- Chloroform in the Reimer-Tiemann reaction
In biological systems, formylation is one of the processes of posttranslational modification in which a formyl group is added to the N-terminus of a protein.
See also
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- This page was last modified on 26 September 2008, at 10:05.
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