GABRG3

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Gamma-aminobutyric acid (GABA) A receptor, gamma 3
Identifiers
Symbols GABRG3;
External IDs OMIM: 600233 MGI: 95624 HomoloGene: 22444
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 2567 14407
Ensembl ENSG00000182256 ENSMUSG00000055026
Uniprot Q99928 P27681
Refseq NM_033223 (mRNA)
NP_150092 (protein)		 NM_177273 (mRNA)
NP_796247 (protein)
Location Chr 15: 24.8 - 25.45 Mb Chr 7: 56.59 - 57.25 Mb
Pubmed search [1] [2]

Gamma-aminobutyric acid (GABA) A receptor, gamma 3, also known as GABRG3, is a human gene.[1]


Contents

See also

References

  1. ^ "Entrez Gene: GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3".

Further reading

  • Greger V, Knoll JH, Woolf E, et al. (1995). "The gamma-aminobutyric acid receptor gamma 3 subunit gene (GABRG3) is tightly linked to the alpha 5 subunit gene (GABRA5) on human chromosome 15q11-q13 and is transcribed in the same orientation.". Genomics 26 (2): 258–64. PMID 7601451. 
  • Tögel M, Mossier B, Fuchs K, Sieghart W (1994). "gamma-Aminobutyric acidA receptors displaying association of gamma 3-subunits with beta 2/3 and different alpha-subunits exhibit unique pharmacological properties.". J. Biol. Chem. 269 (17): 12993–8. PMID 8175718. 
  • Hadingham KL, Wafford KA, Thompson SA, et al. (1996). "Expression and pharmacology of human GABAA receptors containing gamma 3 subunits.". Eur. J. Pharmacol. 291 (3): 301–9. PMID 8719414. 
  • Poulsen CF, Christjansen KN, Hastrup S, Hartvig L (2000). "Identification and cloning of a gamma 3 subunit splice variant of the human GABA(A) receptor.". Brain Res. Mol. Brain Res. 78 (1-2): 201–3. PMID 10891602. 
  • Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression.". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013. 
  • Nymann-Andersen J, Wang H, Chen L, et al. (2002). "Subunit specificity and interaction domain between GABA(A) receptor-associated protein (GABARAP) and GABA(A) receptors.". J. Neurochem. 80 (5): 815–23. PMID 11948245. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Dick DM, Edenberg HJ, Xuei X, et al. (2004). "Association of GABRG3 with alcohol dependence.". Alcohol. Clin. Exp. Res. 28 (1): 4–9. doi:10.1097/01.ALC.0000108645.54345.98. PMID 14745296. 
  • Gole L, Crolla JA, Thomas SN, et al. (2004). "Characterization of breakpoints in the GABRG3 and TSPY genes in a family with a t(Y;15)(p11.2;q12).". Am. J. Med. Genet. A 125 (2): 177–80. doi:10.1002/ajmg.a.20482. PMID 14981720. 

External links

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v • d • e
Ion channel, receptor: ligand-gated ion channels
Cys-loop receptors
5-HT3 (A, B, C, D, E)
GABA A (α1, α2, α3, α4, α5, α6, β1, β2, β3, γ1, γ2, γ3, δ, ε, π, θ) • GABA C (ρ1, ρ2, ρ3)
α1 • α2 • α3 • α4 • β
monomers: α1 • α2 • α3 • α4 • α5 • α6 • α7 • α9 • α10 • β1 • β2 • β3 • β4 • δ • ε
pentamers: (α4)2(β2)3 • (α7)5 • (α1)2(β4)3 - Ganglion type • (α1)2β1δε - Muscle type
Ionotropic glutamates
AMPA (1, 2, 3, 4) • Kainate (1, 2, 3, 4, 5)  • NMDA (1, 2A, 2B, 2C, 2D, 3A, 3B, L1A, L1B)
ATP-gated channels

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