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The ganglion type nicotinic receptor is a type of nicotinic acetylcholine receptor, consisting of the subunit combination (α1)2(β4)3[1].
It is located in the autonomic ganglia, where activation yields EPSP, mainly by increased Na+ and K+ permeability.
Agonists
Nicotinic agonists for this receptor include:
Antagonists
- α-bungarotoxin [2]
- mecamylamine
- trimetaphan
- 18-Methoxycoronaridine
- Bupropion
- Dextromethorphan
- Methadone
References
- ^ Pharmacology, (Rang, Dale, Ritter & Moore, ISBN 0443071454, 5:th ed., Churchill Livingstone 2003) Page 138.
- ^ Neurosci.pharm - MBC 3320 Acetylcholine
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- This page was last modified on 7 July 2008, at 00:19.
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