Ganglionic blocking agents

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A ganglionic blocker (or ganglioplegic) is a type of medication which inhibits postganglionic transmission,[1] primarily by acting as a nicotinic antagonist.[2]

Examples

Examples include hexamethonium, pentolinium, mecamylamine, trimetaphan and pempidine.

Others include:[3]

Uses

Ganglionic blockers are used less frequently now than they were in the past, because more selective agents are now available. However, they are still used in some emergency situations, such as aortic dissection.

References

  1. ^ "Dorlands Medical Dictionary:ganglioplegic".
  2. ^ MeSH Ganglionic+blockers
  3. ^ MeSH list of agents 82005730
Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.
v • d • e
Receptor agonists, antagonists, and reuptake inhibitors
BA/M
AA
ANS
(SANS only—see above for details)
v • d • e
Anticholinergics
Nicotinic antagonists
Ganglionic
Muscarinic antagonists
Presynaptic
acetylcholine synthesis (Hemicholinium-3) · acetylcholine release (Botulinum toxin)
Other
acetylcholinesterase reactivators (Pralidoxime, Obidoxime)
note: in PNS, ganglionic blocker can have direct antinicotinic action at preganglionic terminal, but simulate indirect antimuscarinic activities at postganglionic terminal
v • d • e
Antihypertensives (C02) and diuretics (C03)
Sympatholytic agents
Centrally acting/antiadrenergics
Ganglion-blocking/nicotinic antagonist
Peripherally acting/antiadrenergics
Vasodilators
Other antihypertensives
Diuretics
Other

Wikipedia content modification information:

  • This page was last modified on 24 July 2008, at 04:29.

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