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| Gastric chief cell | |
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| H&E stain of fundic gland polyp showing shortening of the gastric pits with cystic dilatation | |
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| A fundus gland. A. Transverse section of gland. |
A gastric chief cell (or peptic cell, or gastric zymogenic cell) is a cell in the stomach that releases pepsinogen, gastric lipase and rennin. The cell stains basophilic upon H&E prep due to the large proportion of rough endoplasmic reticulum in its cytoplasm.
It works in conjunction with the parietal cell which releases gastric acid, converting the pepsinogen into pepsin.
Nomenclature
The terms "chief cell" and "zymogenic cell" are often used without the word "gastric" to name this type of cell. However those terms can also be used to describe other cell types (for example, parathyroid chief cells.)
See also
External links
- Anatomy Atlases - Microscopic Anatomy, plate 01.05
- Histology at BU 22201loa - "Ultrastructure of the Cell: chief cells and enteroendocrine cell"
- Histology at BU 11304loa - "Digestive System: Alimentary Canal: fundic stomach, gastric glands, base"
- chief cell at Dorland's Medical Dictionary
- Physiology at MCG 6/6ch4/s6ch4_8
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Wikipedia content modification information:
- This page was last modified on 12 October 2008, at 04:06.
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