Gi alpha subunit 3

This MedLibrary.org supplementary page on Gi alpha subunit 3 is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:

Related Sponsors

BM Pharmacy Generic pharmaceuticals at unbeatable prices. Insomnia, men's health, hair health, pain control. bmpharmacy.com
Online Pharmacy Carisoprodol, tadalafil, sildenafil, vardenafil and more... xlpharmacy.com
MedBasket.com Discreet. Inexpensive. Fast shipping. Great selection. What more can we say? medbasket.com
Frugalmed 2000 reasons to shop with us first. frugalmed.com
Ads by Tiva

Identifiers
Symbol GNAI1
Entrez 2770
HUGO 4384
OMIM 139310
RefSeq NM_002069
UniProt P63096
Other data
Locus Chr. 7 q21-q22
Identifiers
Symbol GNAI2
Alt. Symbols GNAI2B
Entrez 2771
HUGO 4385
OMIM 139360
RefSeq NM_002070
UniProt P04899
Other data
Locus Chr. 3 p21
Identifiers
Symbol GNAI3
Entrez 2773
HUGO 4387
OMIM 139370
RefSeq NM_006496
UniProt P08754
Other data
Locus Chr. 1 p13

Gi alpha subunit (or Gi/G0 or Gi protein) is a heterotrimeric G protein subunit which inhibits the production of cAMP from ATP.

Contents

Receptors

The following G-protein coupled receptors couple to the Gi subunit:

Function

Further reading: function of cAMP-dependent protein kinase

Gi inhibits the production of cAMP from ATP, which, in turn, results in decreased activity of cAMP-dependent protein kinase. Thus, the ultimate effect of Gi is thus the opposite of cAMP-dependent protein kinase, which can be found at function of cAMP-dependent protein kinase.

Types

There are several types of Gi: Gia1, Gia2, Gia3 and Gia4

Gia1

Gia1 or Gi1 is encoded by the gene GNAI1.

Gia2

Gia2 or Gi2 is encoded by the gene GNAI2.

Gia3

Gia3 or Gi3 is encoded by the gene GNAI3.

See also

External links

 This biochemistry article is a stub. You can help Wikipedia by expanding it.
v • d • e
Acid anhydride hydrolases: GTPases/G proteins (EC 3.6.5)
3.6.5.1: Heterotrimeric G protein
3.6.5.2: Small GTPase > Ras superfamily
3.6.5.3: Elongation factor
3.6.5.5-6: Other
Dynamin (is a GTPase, is not a G protein) - Tubulin

Wikipedia content modification information:

  • This page was last modified on 15 June 2008, at 13:01.

Wikipedia Authorship and Review

Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.

Wikipedia Usage Guidelines

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Gi alpha subunit 3".

The URL for this specific entry is:

All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.