Glycerol kinase

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glycerol kinase
Identifiers
Symbol GK
Entrez 2710
HUGO 4289
OMIM 300474
RefSeq NM_000167
UniProt P32189
Other data
EC number 2.7.1.30
Locus Chr. X p21.3

Glycerol kinase is a phosphotransferase enzyme involved in lipolysis.

Glycerol kinase catalyzes the transfer of a phosphate from ATP to glycerol thus forming glycerol phosphate. Adipocytes lack glycerol kinase so they cannot metabolize the glycerol produced during triacyl glycerol degradation. This glycerol is instead shuttled to the liver via the blood where it is:

  • phosphorylated by glycerol kinase to glycerol phosphate
  • converted to DHAP (dihydroxyacetone phosphate) which can participate in glycolysis or gluconeogenesis.

See also

External links

References

  • Biochemistry, Champe, P.C., Harvey, R.A., Ferrier, D.R., 3rd ed., 2005.
 This transferase article is a stub. You can help Wikipedia by expanding it.
v • d • e
Transferases: Phosphotransferases/kinases (EC 2.7)
2.7.1 - OH acceptor
2.7.2 - COOH acceptor
2.7.3 - N acceptor
2.7.4 - PO4 acceptor
2.7.6 - P2O7
2.7.7 - nucleotidyl-
2.7.8 - other phos.
2.7.10-11 - protein

Wikipedia content modification information:

  • This page was last modified on 22 November 2007, at 00:57.

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