Haloprogin

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Haloprogin
Systematic (IUPAC) name
1,2,4-trichloro-5-(3-iodoprop-2-ynoxy)benzene
Identifiers
CAS number 777-11-7
ATC code D01AE11
PubChem 3561
DrugBank APRD01011
Chemical data
Formula C9H4Cl3IO 
Mol. mass 361.39
Physical data
Melt. point 113.5 °C (236 °F)
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

Not available in U.S.

Routes Topical

Haloprogin is an antifungal drug used to treat athlete's foot and other fungal infections. It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.

Action

Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over the counter primarily to treat tinea infcections of the skin. The mechanism of action is unknown.[1]

Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.[2]

References

  1. ^ "Haloprogin". Drugs@FDA. Food and Drug Administration. Retrieved on 2007-02-17.
  2. ^ "Haloprogin". DrugBank. University of Alberta (Nov 06, 2006). Retrieved on 2007-02-17.

Wikipedia content modification information:

  • This page was last modified on 19 August 2008, at 19:52.

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