| Haplogroup L5 | |
| Time of origin | 114,200-126,200 YBP[1] |
| Place of origin | East Africa |
| Ancestor | L2'3'4'5'6 |
| Descendants | L5a, L5c |
|---|---|
| Defining mutations | 3423, 7972, 12432, 12950[2] |
In human mitochondrial genetics, Haplogroup L5 is a human mitochondrial DNA (mtDNA) haplogroup. It was previously known as L1e.
Contents |
Origin
Distribution
It is a small African haplogroup from East Africa. The highest frequency is in Mbuti Pygmies at 15%.[3] It is present in relatively small frequencies in Tanzania (Sandawe and others), Kenya, Ethiopia, Sudan, Nubia, Egypt and Saudi Arabia.[4]
Subclades
Tree
This phylogenetic tree of haplogroup L5 subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[2] and subsequent published research.
- Most Recent Common Ancestor (MRCA)
- L1-6
- L2-6
- L5
- L5a
- L5a1
- L5a1a
- L5a1b
- L5a1c
- L5a2
- L5a1
- L5c
- L5c1
- L5c2
- L5a
- L5
- L2-6
- L1-6
References
- ^ Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock. 2009. doi:10.1016/j.ajhg.2009.05.001. http://www.cell.com/AJHG/abstract/S0002-9297(09)00163-3.
- ^ a b van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation 30 (2): E386-E394. PMID 18853457 doi:10.1002/humu.20921. http://www3.interscience.wiley.com/journal/121449735/abstract?CRETRY=1&SRETRY=0. Retrieved 2009-05-20.
- ^ Sarah A. Tishkoff et al. 2007, History of Click-Speaking Populations of Africa Inferred from mtDNA and Y Chromosome Genetic Variation. Molecular Biology and Evolution 2007 24(10):2180-2195
- ^ Abu-Amero et al. 2008 February. "Mitochondrial DNA structure in the Arabian Peninsula", BMC Evolutionary Biology. 8(45): 52.
| Mitochondrial Eve (L) | ||||||||||||||||||||||||||||||||
| L0 | L1 | L2 | L3 | L4 | L5 | L6 | ||||||||||||||||||||||||||
| M | N | |||||||||||||||||||||||||||||||
| CZ | D | E | G | Q | A | S | R | I | W | X | Y | |||||||||||||||||||||
| C | Z | B | F | R0 | pre-JT | P | U | |||||||||||||||||||||||||
| HV | JT | K | ||||||||||||||||||||||||||||||
| H | V | J | T | Former Clusters IWX | ||||||||||||||||||||||||||||
External links
- General
- Ian Logan's Haplogroups L5.
- Mannis van Oven's Phylotree
Open source encyclopedia content modification information:
This page was last modified on 16 December 2009 at 07:08.
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Haplogroup L5 (mtDNA)", which is available in its original form here:
http://en.wikipedia.org/w/index.php?title=Haplogroup_L5_(mtDNA)
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