Histidine decarboxylase

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histidine decarboxylase
Identifiers
Symbol HDC
Entrez 3067
HUGO 4855
OMIM 142704
RefSeq NM_002112
UniProt P19113
Other data
EC number 4.1.1.22
Locus Chr. 15 q21-q22

Histidine decarboxylase (HDC) is the enzyme that catalyzes the reaction which produces histamine from histidine as follows:

C6H9N3O2 → C5H9N3 + CO2

Conversion of histidine to histamine by histidine decarboxylase
Conversion of histidine to histamine by histidine decarboxylase

External links

 This lyase article is a stub. You can help Wikipedia by expanding it.
v • d • e
Carbon-carbon lyases (EC 4.1)
4.1.1: Carboxy-lyases
4.1.2: Aldehyde-lyases
4.1.3: Oxo-acid-lyases
v • d • e
Metabolism: amino acid metabolism - neurotransmitter enzymes
histidine→histamine
anabolism: Histidine decarboxylase
catabolism: Histamine N-methyltransferase - Amine oxidase
tyrosine→dopamine→epinephrine
glutamate→GABA
tryptophan→serotonin→melatonin
arginine→NO
choline→Acetylcholine
see also intermediates

Wikipedia content modification information:

  • This page was last modified on 24 May 2008, at 01:51.

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