This MedLibrary.org supplementary page on Homatropine is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:
Related Sponsors
 |
|
|
Homatropine
|
|
| Systematic (IUPAC) name | |
| (N,N-dimethyl-8-azoniabicyclo[3.2.1]oct-3-yl) 2-hydroxy-2-phenyl-acetate bromide | |
| Identifiers | |
| CAS number | |
| ATC code | A02 S01 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C16H22BrNO3 |
| Mol. mass | 356.26 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Homatropine (Equipin, Isopto Homatropine) is an anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic, to temporarily paralyze accommodation, and as a mydriatic, to dilate the pupil.
Homatropine is less potent than atropine and has a shorter duration of action. It is available as the hydrobromide or methylbromide salt.
Certain preparations of drugs such as hydrocodone are mixed with a small, sub-theraputic amount homatropine methylbromide to discourage intentional overdose. [1]
Homatropine is also given as an atropine substitute given to reverse the muscarinic and CNS effects associated with indirect cholinomimetic (anti-AChase) administration.
Side effects
- Blurred vision
- Sensitivity to light
Contraindications
- Untreated glaucoma
- Myasthenia gravis
- Severe heart failure
- Thyrotoxicosis
References
|
||||||||
 |
This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
Wikipedia content modification information:
- This page was last modified on 20 July 2008, at 23:04.
Wikipedia Authorship and Review
Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.
Wikipedia Usage Guidelines
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Homatropine".
The URL for this specific entry is:
All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.