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| Hurthle cell Classification and external resources |
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| ICD-10 | C73.9 |
|---|---|
| ICD-O: | 8290/0 |
| DiseasesDB | 31956 |
| eMedicine | med/1045 |
| MeSH | D018249 |
A Hürthle cell (also known, incorrectly as Askanazy cell. Askanazy cells are interfollicular C-cells) is an oncocytic cell in the thyroid that is often associated with Hashimoto's thyroiditis as well as follicular thyroid cancer.
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Histology
Hürthle cells are characterized as enlarged epithelial cells with abundant eosinophilic granular cytoplasm as a result of altered mitochondria.[1] They generally stain pink and are prominently found in histological sections of thyroid glands affected with Hashimoto's.
Clinical significance
A Hürthle cell adenoma is a well-differentiated type of follicular thyroid adenoma (benign tumor) that, in rare cases, has the potential to become malignant and metastasize (Hürthle cell carcinoma).
Eponym
It is named for Karl Hürthle.[2][3]
See also
References
- ^ Aytug, Serhat (June 13, 2006). "Hurthle Cell Carcinoma". eMedicine.
- ^ synd/2742 at Who Named It
- ^ M. Askanazy. Pathologisch-anatomische Beiträge zur Kenntniss des morbus basedowii, insbesondere uber die dabei auftretende Muskelerkrankkung. Deutsches Archiv für klinische Medicin, Leipzig, 1898, 61:118-186.
External links
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- This page was last modified on 12 October 2008, at 08:38.
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