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| IBMX | |
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| IUPAC name | 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione |
| Other names | 3-Isobutyl-1-methylxanthine |
| Identifiers | |
| CAS number | [28822-58-4] |
| PubChem | |
| SMILES |
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| Properties | |
| Molecular formula | C10H14N4O2 |
| Molar mass | 222.3 g/mol |
| Appearance | White solid |
| Melting point |
199-201 °C |
| Solubility | Soluble in ethanol, DMSO, and methanol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references |
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IBMX, isobutylmethylxanthine, is a non-specific inhibitor of phosphodiesterases (PDEs) (IC50 = 2-50 μM) [1] except PDE8 and PDE9 [2]. It also possesses adenosine antagonist activity.[3][4]
References
- ^ J.A.Beavo et al. Mol. Pharmacol. 1970 6 597
- ^ Soderling and Beavo Current Opinion in Cell Biol. 2000 12 174
- ^ Bruns et al. Mol. Pharmacol. 1986 29 331
- ^ Coffin et al. Eur. J. Pharmacol. 1989 170 35
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