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Contents 1 C00-D48 - Neoplasms 2 D50-D89 - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism 2.1 (D50-D53) Nutritional anemias 2.2 (D55-D59) Haemolytic anaemias 2.3 (D60-D64) Aplastic and other anaemias 2.4 (D65-D69) Coagulation defects, purpura and other haemorrhagic conditions 2.5 (D70-D77) Other diseases of blood and blood-forming organs 2.6 (D80-D89) Certain disorders involving the immune mechanism 3 See also

C00-D48 - Neoplasms

see now ICD-10 Chapter II: Neoplasms

D50-D89 - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

(D50-D53) Nutritional anemias

• (D50.) Iron deficiency anaemia
  • (D50.0) Iron deficiency anaemia secondary to blood loss (chronic)
  • (D50.1) Sideropenic dysphagia
    • Kelly-Paterson syndrome
    • Plummer-Vinson syndrome
  • (D50.8) Other iron deficiency anaemias
  • (D50.9) Iron deficiency anaemia, unspecified

• (D51.) Vitamin B12 deficiency anaemia
  • (D51.0) Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
    • Pernicious anemia
  • (D51.1) Vitamin B 12 deficiency anaemia due to selective vitamin B 12 malabsorption with proteinuria
    • Megaloblastic hereditary anaemia
  • (D51.2) Transcobalamin II deficiency
  • (D51.3) Other dietary vitamin B 12 deficiency anaemia
  • (D51.8) Other vitamin B 12 deficiency anaemias
  • (D51.9) Vitamin B 12 deficiency anaemia, unspecified

• (D52.) Folate deficiency anaemia
  • (D52.0) Dietary folate deficiency anaemia
    • Nutritional megaloblastic anaemia
  • (D52.1) Drug-induced folate deficiency anaemia
  • (D52.8) Other folate deficiency anaemias
  • (D52.9) Folate deficiency anaemia, unspecified

• (D53.) Other nutritional anaemias
  • (D53.0) Protein deficiency anaemia
  • (D53.1) Other megaloblastic anaemias, not elsewhere classified
  • (D53.2) Scorbutic anaemia
  • (D53.8) Other specified nutritional anaemias
  • (D53.9) Nutritional anaemia, unspecified

(D55-D59) Haemolytic anaemias

• (D55.) Anaemia due to enzyme disorders
  • (D55.0) Anaemia due to glucose-6-phosphate dehydrogenase (G6PD) deficiency
    • Favism
    • G6PD deficiency anaemia
  • (D55.1) Anaemia due to other disorders of glutathione metabolism
  • (D55.2) Anaemia due to disorders of glycolytic enzymes
    • hexokinase deficiency
    • pyruvate kinase deficiency
    • triose-phosphate isomerase deficiency
  • (D55.3) Anaemia due to disorders of nucleotide metabolism
  • (D55.8) Other anaemias due to enzyme disorders
  • (D55.9) Anaemia due to enzyme disorder, unspecified

• (D56.) Thalassaemia
  • (D56.0) Alpha thalassaemia
  • (D56.1) Beta thalassaemia
  • (D56.2) Delta-beta thalassaemia
  • (D56.3) Thalassaemia trait
  • (D56.4) Hereditary persistence of fetal haemoglobin (HPFH)
  • (D56.8) Other thalassaemias
  • (D56.9) Thalassaemia, unspecified

• (D57.) Sickle-cell disorders
  • (D57.0) Sickle-cell anaemia with crisis
  • (D57.1) Sickle-cell anaemia without crisis
  • (D57.2) Double heterozygous sickling disorders
  • (D57.3) Sickle-cell trait
  • (D57.8) Other sickle-cell disorders

• (D58.) Other hereditary haemolytic anaemias
  • (D58.0) Hereditary spherocytosis
    • Acholuric (familial) jaundice
    • Congenital (spherocytic) haemolytic icterus
    • Minkowski-Chauffard syndrome
  • (D58.1) Hereditary elliptocytosis
    • Elliptocytosis (congenital)
    • Ovalocytosis (congenital)(hereditary)
  • (D58.2) Other haemoglobinopathies
    • Abnormal haemoglobin NOS
    • Congenital Heinz body anaemia
    • Haemoglobinopathy NOS
    • Unstable haemoglobin haemolytic disease
  • (D58.8) Other specified hereditary haemolytic anaemias
    • Stomatocytosis

• (D59.) Acquired haemolytic anaemia
  • (D59.0) Drug-induced autoimmune haemolytic anaemia
  • (D59.1) Other autoimmune haemolytic anaemias
    • Warm autoimmune hemolytic anemia
  • (D59.2) Drug-induced nonautoimmune haemolytic anaemia
  • (D59.3) Haemolytic-uraemic syndrome
  • (D59.4) Other nonautoimmune haemolytic anaemias
    • Microangiopathic hemolytic anemia
  • (D59.5) Paroxysmal nocturnal haemoglobinuria (Marchiafava-Micheli)
  • (D59.6) Haemoglobinuria due to haemolysis from other external causes
    • paroxysmal cold haemoglobinuria
  • (D59.8) Other acquired haemolytic anaemias
  • (D59.9) Acquired haemolytic anaemia, unspecified

(D60-D64) Aplastic and other anaemias

• (D60.) Acquired pure red cell aplasia (erythroblastopenia)
• (D61.) Other aplastic anaemias
  • (D61.0) Constitutional aplastic anaemia
    • Fanconi anemia
• (D62.) Acute posthaemorrhagic anaemia
• (D63.) Anaemia in chronic diseases classified elsewhere

• (D64.) Other anaemias
  • (D64.0) Hereditary sideroblastic anaemia
  • (D64.1) Secondary sideroblastic anaemia due to disease
  • (D64.2) Secondary sideroblastic anaemia due to drugs and toxins
  • (D64.3) Other sideroblastic anaemias
  • (D64.4) Congenital dyserythropoietic anaemia
  • (D64.8) Other specified anaemias
  • (D64.9) Anaemia, unspecified

(D65-D69) Coagulation defects, purpura and other haemorrhagic conditions

• (D65.) Disseminated intravascular coagulation (defibrination syndrome)
  • Afibrinogenaemia, acquired
  • Consumption coagulopathy
  • Diffuse or disseminated intravascular coagulation (DIC)
  • Fibrinolytic haemorrhage, acquired
  • Fibrinolytic purpura
  • Purpura fulminans

• (D66.) Hereditary factor VIII deficiency
  • Haemophilia A

• (D67.) Hereditary factor IX deficiency
  • Christmas disease

• (D68.) Other coagulation defects
  • (D68.0) Von Willebrand's disease
  • (D68.1) Hereditary factor XI deficiency
    • Haemophilia C
  • (D68.2) Hereditary deficiency of other clotting factors
  • (D68.3) Haemorrhagic disorder due to circulating anticoagulants
  • (D68.4) Acquired coagulation factor deficiency
  • (D68.8) Other specified coagulation defects
  • (D68.9) Coagulation defect, unspecified

• (D69.) Purpura and other haemorrhagic conditions
  • (D69.0) Allergic purpura
    • anaphylactoid purpura
    • Henoch-Schönlein purpura
  • (D69.1) Qualitative platelet defects
    • Bernard-Soulier syndrome (giant platelet)
    • Glanzmann's disease
    • Grey platelet syndrome
    • Thromboasthenia (haemorrhagic)(hereditary)
    • Thrombocytopathy
  • (D69.2) Other nonthrombocytopenic purpura
  • (D69.3) Idiopathic thrombocytopenic purpura
    • Evans' syndrome
  • (D69.4) Other primary thrombocytopenia
  • (D69.5) Secondary thrombocytopenia
  • (D69.6) Thrombocytopenia, unspecified
  • (D69.8) Other specified haemorrhagic conditions
  • (D69.9) Haemorrhagic condition, unspecified

(D70-D77) Other diseases of blood and blood-forming organs

• (D70.) Agranulocytosis
  • Agranulocytic angina
  • Infantile genetic agranulocytosis
  • Kostmann's disease
  • Neutropenia, NOS

• (D71.) Functional disorders of polymorphonuclear neutrophils
  • Cell membrane receptor complex (CR3) defect
  • Chronic (childhood) granulomatous disease
  • Congenital dysphagocytosis
  • Progressive septic granulomatosis

• (D72.) Other disorders of white blood cells
  • (D72.0) Genetic anomalies of leukocytes
    • Alder anomaly
    • May-Hegglin anomaly
    • Pelger-Huët anomaly
  • (D72.1) Eosinophilia
  • (D72.8) Other specified disorders of white blood cells
    • Leukaemoid reaction: lymphocytic, monocytic, myelocytic
    • Leukocytosis
    • Lymphocytosis (symptomatic)
    • Lymphopenia
    • Monocytosis (symptomatic)
    • Plasmacytosis
  • (D72.9) Disorder of white blood cells, unspecified

• (D73.) Diseases of spleen
  • (D73.0) Hyposplenism
  • (D73.1) Hypersplenism
  • (D73.2) Chronic congestive splenomegaly
  • (D73.3) Abscess of spleen
  • (D73.4) Cyst of spleen
  • (D73.5) Infarction of spleen
  • (D73.8) Other diseases of spleen
  • (D73.9) Disease of spleen, unspecified

• (D74.) Methaemoglobinaemia
  • (D74.0) Congenital methaemoglobinaemia
    • Congenital NADH-methaemoglobin reductase deficiency
    • Haemoglobin-M (Hb-M) disease
    • Methaemoglobinaemia, hereditary
  • (D74.8) Other methaemoglobinaemias
    • Acquired methaemoglobinaemia (with sulfhaemoglobinaemia)
    • Toxic methaemoglobinaemia
  • (D74.9) Methaemoglobinaemia, unspecified

• (D75.) Other diseases of blood and blood-forming organs
  • (D75.0) Familial erythrocytosis
  • (D75.1) Secondary polycythaemia
  • (D75.2) Essential thrombocytosis
  • (D75.8) Other specified diseases of blood and blood-forming organs
    • Basophilia
  • (D75.9) Disease of blood and blood-forming organs, unspecified

• (D76.) Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
  • (D76.0) Langerhans' cell histiocytosis, not elsewhere classified
    • Eosinophilic granuloma
    • Hand-Schüller-Christian disease
    • Histiocytosis X (chronic)
  • (D76.1) Haemophagocytic lymphohistiocytosis
    • Familial haemophagocytic reticulosis
  • (D76.2) Haemophagocytic syndrome, infection-associated
  • (D76.3) Other histiocytosis syndromes
    • Reticulohistiocytoma (giant-cell)
    • Sinus histiocytosis with massive lymphadenopathy
    • Xanthogranuloma

• (D77.) Other disorders of blood and blood-forming organs in diseases classified elsewhere

(D80-D89) Certain disorders involving the immune mechanism

• (D80.) Immunodeficiency with predominantly antibody defects
  • (D80.0) Hereditary hypogammaglobulinaemia
    • Autosomal recessive agammaglobulinaemia (Swiss type)
    • X-linked agammaglobulinaemia (Bruton) (with growth hormone deficiency)
  • (D80.1) Nonfamilial hypogammaglobulinaemia
    • Agammaglobulinaemia with immunoglobulin-bearing B-lymphocytes
    • Common variable agammaglobulinaemia (CVAgamma)
    • Hypogammaglobulinaemia NOS
  • (D80.2) Selective deficiency of immunoglobulin A (IgA)
  • (D80.3) Selective deficiency of immunoglobulin G (IgG) subclasses
  • (D80.4) Selective deficiency of immunoglobulin M (IgM)
  • (D80.5) Immunodeficiency with increased immunoglobulin M (IgM)
  • (D80.6) Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
  • (D80.7) Transient hypogammaglobulinaemia of infancy
  • (D80.8) Other immunodeficiencies with predominantly antibody defects
    • Kappa light chain deficiency
  • (D80.8) Immunodeficiency with predominantly antibody defects, unspecified

• (D81.) Combined immunodeficiencies
  • (D81.0) Severe combined immunodeficiency (SCID) with reticular dysgenesis
  • (D81.1) Severe combined immunodeficiency (SCID) with low T-cell and B-cell numbers
  • (D81.2) Severe combined immunodeficiency (SCID) with low or normal B-cell numbers
  • (D81.3) Adenosine deaminase deficiency (ADA)
  • (D81.4) Nezelof's syndrome
  • (D81.5) Purine nucleoside phosphorylase deficiency (PNP)
  • (D81.6) Major histocompatibility complex class I deficiency
    • Bare lymphocyte syndrome
  • (D81.7) Major histocompatibility complex class II deficiency
  • (D81.8) Other combined immunodeficiencies
    • Biotin-dependent carboxylase deficiency
  • (D81.9) Combined immunodeficiency, unspecified
    • Severe combined immunodeficiency disorder (SCID) NOS

• (D82.) Immunodeficiency associated with other major defects
  • (D82.0) Wiskott-Aldrich syndrome
    • Immunodeficiency with thrombocytopenia and eczema
  • (D82.1) Di George's syndrome
  • (D82.2) Immunodeficiency with short-limbed stature
  • (D82.3) Immunodeficiency following hereditary defective response to Epstein-Barr virus
    • X-linked lymphoproliferative disease
  • (D82.4) Hyperimmunoglobulin E syndrome (IgE)
• (D83.) Common variable immunodeficiency

• (D84.) Other immunodeficiencies
  • (D84.0) Lymphocyte function antigen-1 (LFA-1) defect
  • (D84.1) Defects in the complement system
    • C1 esterase inhibitor deficiency (C1-INH)
  • (D84.8) Other specified immunodeficiencies
  • (D84.9) Immunodeficiency, unspecified

• (D86.) Sarcoidosis
  • (D86.0) Sarcoidosis of lung
  • (D86.1) Sarcoidosis of lymph nodes
  • (D86.2) Sarcoidosis of lung with sarcoidosis of lymph nodes
  • (D86.3) Sarcoidosis of skin
  • (D86.8) Sarcoidosis of other and combined sites
• (D89.) Other disorders involving the immune mechanism, not elsewhere classified
  • (D89.0) Polyclonal hypergammaglobulinaemia
    • Benign hypergammaglobulinaemic purpura
    • Polyclonal gammopathy NOS
  • (D89.1) Cryoglobulinaemia
  • (D89.2) Hypergammaglobulinaemia, unspecified
  • (D89.8) Other specified disorders involving the immune mechanism, not elsewhere classified
  • (D89.9) Disorder involving the immune mechanism, unspecified

See also

• List of ICD-10 codes
• International Statistical Classification of Diseases and Related Health Problems
• List of ICD-9 codes 140-239: Neoplasms

v • d • e Pathology: Tumor, Neoplasm, Cancer, and Oncology (C00-D48, 140-239) Benign tumors Hyperplasia - Cyst - Pseudocyst - Hamartoma - Benign tumor Malignant progression Dysplasia - Carcinoma in situ - Cancer - Metastasis Topography Oral - Head/Neck - Nasopharyngeal - digestive system - Respiratory system - Bone - Skin - Blood - Urogenital - Nervous system - Endocrine system Histology Carcinoma - Sarcoma - Papilloma - Adenoma Misc. Tumor suppressor genes/oncogenes - Staging/grading - Carcinogenesis - Carcinogen - Research - Paraneoplastic syndrome - List of oncology-related terms

v • d • e Pathology: hematology · myeloid hematologic disease (primarily D50-D77 · 280-289) RBCs/ hemoglobinopathy + Polycythemia · Macrocytosis  · Anemia Nutritional Iron deficiency anemia (Plummer-Vinson syndrome) · Megaloblastic anemia (Pernicious anemia) Hemolytic Hereditary enzyme: G6PD Deficiency · Pyruvate kinase deficiency · Triosephosphate isomerase deficiency hemoglobin: Thalassemia · Sickle-cell disease/trait membrane: Hereditary spherocytosis · Hereditary elliptocytosis · Hereditary stomatocytosis Acquired Autoimmune (Warm, Cold) · HUS · MAHA · PNH · PCH · Myelophthisic Aplastic Acquired PRCA · Diamond-Blackfan anemia · Fanconi anemia · Sideroblastic anemia Blood tests Normocytic · Microcytic · Macrocytic · Normochromic · Hypochromic Other Methemoglobinemia Coagulation/platelets/ coagulopathy/ bleeding diathesis + Hypercoagulability primary: Antithrombin III deficiency · Protein C deficiency/Activated protein C resistance/Protein S deficiency/Factor V Leiden · Hyperprothrombinemia acquired: DIC (Congenital afibrinogenemia, Purpura fulminans) · autoimmune (Antiphospholipid) Other Essential thrombocytosis  · clotting factor: Hemophilia (A/VIII, B/IX, C/XI) • Von Willebrand disease • Hypoprothrombinemia/II · XIII platelet function: Bernard-Soulier syndrome · Glanzmann's thrombasthenia · Hermansky-Pudlak syndrome · Gray platelet syndrome · May Hegglin anomaly · Pelger-Huet anomaly Purpura: Henoch-Schönlein · TP · ITP (Evans syndrome) · TTP Thrombocytopenia (Heparin-induced thrombocytopenia) Monocytes/ macrophages + Histiocytosis WHO-I (Langerhans cell histiocytosis) WHO-II/non-Langerhans-cell (Juvenile xanthogranuloma, Hemophagocytic lymphohistiocytosis) WHO-III/malignant (Acute monocytic leukemia, Malignant histiocytosis, Erdheim-Chester disease) Other Chronic granulomatous disease -cytosis: Monocytosis  · -penia: Monocytopenia Granulocytes + -cytosis: granulocytosis (Neutrophilia, Eosinophilia, Basophilia)  · <