IL-3 receptor

This MedLibrary.org supplementary page on IL-3 receptor is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:

Related Sponsors

BM Pharmacy Generic pharmaceuticals at unbeatable prices. Insomnia, men's health, hair health, pain control. bmpharmacy.com
Online Pharmacy Carisoprodol, tadalafil, sildenafil, vardenafil and more... xlpharmacy.com
MedBasket.com Discreet. Inexpensive. Fast shipping. Great selection. What more can we say? medbasket.com
Frugalmed 2000 reasons to shop with us first. frugalmed.com
Ads by Tiva

Identifiers
Symbol IL3RA
Alt. Symbols CD123
HUGO 6012
OMIM 308385
Other data
Locus Chr. X p22.3
interleukin 3 receptor, Y-Chromosomal
Identifiers
Symbol IL3RA
Alt. Symbols IL3RY, IL3RAY
Entrez 3563
HUGO 6012
OMIM 430000
Other data
Locus Chr. Y p11.3

The interleukin-3 receptor (also known as CD123 antigen) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune system.

The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes.

The receptor belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit.

The gene for the alpha subunit is 40 kilobases long and has 12 exons.

The receptor, found on pluripotent progenitor cells, induces tyrosine phosphorylation within the cell and promotes proliferation and differentiation within the hematopoietic cell lines.

External links

v • d • e
Transmembrane receptors: immune receptors
Cytokine receptor
Other
Other endogenous
Other
Exogenous
Antigen receptor
Other
 This immunology article is a stub. You can help Wikipedia by expanding it.

Wikipedia content modification information:

  • This page was last modified on 21 May 2008, at 17:17.

Wikipedia Authorship and Review

Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.

Wikipedia Usage Guidelines

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "IL-3 receptor".

The URL for this specific entry is:

All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.