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Ibopamine
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| Systematic (IUPAC) name | |
| 4-(2-(methylamino)ethyl)-1,2-
phenylene bis(2-methylpropanoate) |
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| Identifiers | |
| CAS number | |
| ATC code | C01 S01 |
| PubChem | |
| Chemical data | |
| Formula | C17H25NO4 |
| Mol. mass | 307.385 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Ibopamine is a sympathomimetic used in ophthalmology.[1]
It also has been investigated for use in the treatment of congestive heart failure.[3]
It acts on dopaminergic receptors.[4][5]
It also acts upon adrenergic receptors.[6]
See also
References
- ^ Magacho L, Costa ML, Dessimoni A, de Avila MP (2006). "Comparison between the 1% and 2% ibopamine provocative test in primary open-angle glaucoma patients: sensitivity, specificity and tolerability". Arq Bras Oftalmol 69 (5): 695–9. PMID 17187138.
- ^ Marchini G, Babighian S, Tosi R, Perfetti S, Bonomi L (June 2001). "Effects of 2% ibopamine on pupil, refraction, anterior segment anatomy and intraocular pressure". J Ocul Pharmacol Ther 17 (3): 215–23. doi:. PMID 11436942.
- ^ van Veldhuisen DJ, Man in 't Veld AJ, Dunselman PH, et al (November 1993). "Double-blind placebo-controlled study of ibopamine and digoxin in patients with mild to moderate heart failure: results of the Dutch Ibopamine Multicenter Trial (DIMT)". J. Am. Coll. Cardiol. 22 (6): 1564–73. PMID 7901256.
- ^ Metra M, Missale C, Spano PF, Cas LD (May 1995). "Dopaminergic drugs in congestive heart failure: hemodynamic and neuroendocrine responses to ibopamine, dopamine, and dihydroergotoxine". J. Cardiovasc. Pharmacol. 25 (5): 732–40. PMID 7630152.
- ^ Lieverse AG, Girbes AR, Van Veldhuisen DJ, et al (July 1995). "The effects of ibopamine on glomerular filtration rate and plasma norepinephrine remain preserved during prolonged treatment in patients with congestive heart failure". Eur. Heart J. 16 (7): 937–42. PMID 7498209.
- ^ "IngentaConnect Ibopamine Stimulates -Adrenergic Receptors and D1 Dopaminergic Re...".
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Wikipedia content modification information:
- This page was last modified on 18 July 2008, at 02:49.
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