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Kininogens are proteins that are defined by their role as precursors for kinin, but that also can have additional roles.
The two main types are:
- High-molecular-weight kininogen, which is produced by the liver together with prekallikrein. It acts mainly as a cofactor on coagulation and inflammation, and has no intrinsic catalytic activity.
- Low-molecular-weight kininogen, which is produced locally by numerous tissues, and secreted together with tissue kallikrein.
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- This page was last modified on 22 January 2008, at 01:16.
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