Lercanidipine

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Lercanidipine
Systematic (IUPAC) name
methyl[2-(3,3-diphenylpropyl-methyl-amino)- 1,1-dimethyl-ethyl] 2,6-dimethyl- 4-(3-nitrophenyl)- 1,4-dihydropyridine-3, 5-dicarboxylate
Identifiers
CAS number 100427-26-7
ATC code C08CA13
PubChem 65866
DrugBank APRD00193
Chemical data
Formula C36H41N3O6 
Mol. mass 611.727 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Lercanidipine is a calcium channel blocker of the dihydropyridine class.

It is sold under various commercial names including Zanidip.

Further reading

  • Lin T, Voon W, Yen H, Huang C, Su H, Lai W, Sheu S (2006). "Lercanidipine and losartan effects on blood pressure and fibrinolytic parameters.". Kaohsiung J Med Sci 22 (4): 177–83. PMID 16679299. 
  • Martinez M, Lopes L, Coelho E, Nobre F, Rocha J, Gerlach R, Tanus-Santos J (2006). "Lercanidipine reduces matrix metalloproteinase-9 activity in patients with hypertension.". J Cardiovasc Pharmacol 47 (1): 117–22. doi:10.1097/01.fjc.0000196241.96759.71. PMID 16424795. 
  • Agrawal R, Marx A, Haller H (2006). "Efficacy and safety of lercanidipine versus hydrochlorothiazide as add-on to enalapril in diabetic populations with uncontrolled hypertension.". J Hypertens 24 (1): 185–92. doi:10.1097/01.hjh.0000198987.34588.11. PMID 16331117. 

External links

v • d • e
Calcium channel blockers (C08)
Dihydropyridines
Phenylalkylamines
Benzothiazepines
Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

Wikipedia content modification information:

  • This page was last modified on 31 May 2008, at 14:25.

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