MYL6B

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Myosin, light chain 6B, alkali, smooth muscle and non-muscle
PDB rendering based on 1oe9.
Available structures: 1oe9, 1w7i, 1w7j
Identifiers
Symbols MYL6B; MLC1SA
External IDs OMIM: 609930 MGI: 1917789 HomoloGene: 86887
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 140465 216459
Ensembl ENSG00000196465 ENSMUSG00000039824
Uniprot P14649 Q8CI43
Refseq NM_002475 (mRNA)
NP_002466 (protein)		 XM_978382 (mRNA)
XP_983476 (protein)
Location Chr 12: 54.83 - 54.84 Mb Chr 10: 127.9 - 127.9 Mb
Pubmed search [1] [2]

Myosin, light chain 6B, alkali, smooth muscle and non-muscle, also known as MYL6B, is a human gene.[1]

Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue.[1]

References

  1. ^ a b "Entrez Gene: MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle".

Further reading

  • Coureux PD, Sweeney HL, Houdusse A (2005). "Three myosin V structures delineate essential features of chemo-mechanical transduction.". EMBO J. 23 (23): 4527-37. doi:10.1038/sj.emboj.7600458. PMID 15510214. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Komiyama M, Soldati T, von Arx P, Perriard JC (1997). "The intracompartmental sorting of myosin alkali light chain isoproteins reflects the sequence of developmental expression as determined by double epitope-tagging competition.". J. Cell. Sci. 109 ( Pt 8): 2089-99. PMID 8856505. 
  • Zimmermann K, Starzinski-Powitz A (1990). "A novel isoform of myosin alkali light chain isolated from human muscle cells.". Nucleic Acids Res. 17 (24): 10496. PMID 2602161. 
  • Seidel U, Bober E, Winter B, et al. (1988). "Alkali myosin light chains in man are encoded by a multigene family that includes the adult skeletal muscle, the embryonic or atrial, and nonsarcomeric isoforms.". Gene 66 (1): 135-46. PMID 2458299. 
  • Hailstones DL, Gunning PW (1990). "Characterization of human myosin light chains 1sa and 3nm: implications for isoform evolution and function.". Mol. Cell. Biol. 10 (3): 1095-104. PMID 2304459. 
 This article on a gene on chromosome 12 is a stub. You can help Wikipedia by expanding it.

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  • This page was last modified on 7 July 2008, at 22:25.

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