MYLIP

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Myosin regulatory light chain interacting protein
Identifiers
Symbols MYLIP; MIR
External IDs OMIM: 610082 MGI: 2388271 HomoloGene: 8309
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 29116 218203
Ensembl ENSG00000007944 ENSMUSG00000038175
Uniprot Q8WY64 Q3TAE7
Refseq NM_013262 (mRNA)
NP_037394 (protein)		 XM_978411 (mRNA)
XP_983505 (protein)
Location Chr 6: 16.24 - 16.26 Mb Chr 13: 45.4 - 45.42 Mb
Pubmed search [1] [2]

Myosin regulatory light chain interacting protein, also known as MYLIP, is a human gene.[1]

The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP) is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth.[1]

References

  1. ^ a b "Entrez Gene: MYLIP myosin regulatory light chain interacting protein".

Further reading

  • Olsson PA, Korhonen L, Mercer EA, Lindholm D (2000). "MIR is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth.". J. Biol. Chem. 274 (51): 36288–92. PMID 10593918. 
  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. PMID 11042152. 
  • Olsson PA, Bornhauser BC, Korhonen L, Lindholm D (2001). "Neuronal expression of the ERM-like protein MIR in rat brain and its localization to human chromosome 6.". Biochem. Biophys. Res. Commun. 279 (3): 879–83. doi:10.1006/bbrc.2000.4028. PMID 11162443. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Bornhauser BC, Olsson PA, Lindholm D (2003). "MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain.". J. Biol. Chem. 278 (37): 35412–20. doi:10.1074/jbc.M306271200. PMID 12826659. 
  • Bornhauser BC, Johansson C, Lindholm D (2003). "Functional activities and cellular localization of the ezrin, radixin, moesin (ERM) and RING zinc finger domains in MIR.". FEBS Lett. 553 (1-2): 195–9. PMID 14550572. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression.". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMID 15498874. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Ohmura-Hoshino M, Matsuki Y, Aoki M, et al. (2006). "Inhibition of MHC class II expression and immune responses by c-MIR.". J. Immunol. 177 (1): 341–54. PMID 16785530. 
 This article on a gene on chromosome 6 is a stub. You can help Wikipedia by expanding it.

Wikipedia content modification information:

  • This page was last modified on 9 July 2008, at 02:20.

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