MYO9B

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Myosin IXB
Identifiers
Symbols MYO9B; CELIAC4; MYR5
External IDs OMIM: 602129 MGI: 106624 HomoloGene: 3058
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 4650 17925
Ensembl ENSG00000099331 ENSMUSG00000004677
Uniprot Q13459 Q3TRQ0
Refseq NM_004145 (mRNA)
NP_004136 (protein)		 NM_015742 (mRNA)
NP_056557 (protein)
Location Chr 19: 17.07 - 17.19 Mb Chr 8: 74.22 - 74.29 Mb
Pubmed search [1] [2]

Myosin IXB, also known as MYO9B, is a human gene.[1]


References

  1. ^ "Entrez Gene: MYO9B myosin IXB".

Further reading

  • Bement WM, Hasson T, Wirth JA, et al. (1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.". Proc. Natl. Acad. Sci. U.S.A. 91 (14): 6549–53. PMID 8022818. 
  • Wirth JA, Jensen KA, Post PL, et al. (1997). "Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail.". J. Cell. Sci. 109 ( Pt 3): 653–61. PMID 8907710. 
  • Bähler M, Kehrer I, Gordon L, et al. (1997). "Physical mapping of human myosin-IXB (MYO9B), the human orthologue of the rat myosin myr 5, to chromosome 19p13.1.". Genomics 43 (1): 107–9. doi:10.1006/geno.1997.4776. PMID 9226381. 
  • Post PL, Bokoch GM, Mooseker MS (1998). "Human myosin-IXb is a mechanochemically active motor and a GAP for rho.". J. Cell. Sci. 111 ( Pt 7): 941–50. PMID 9490638. 
  • Grewal PK, Jones AM, Maconochie M, et al. (2000). "Cloning of the murine unconventional myosin gene Myo9b and identification of alternative splicing.". Gene 240 (2): 389–98. PMID 10580159. 
  • Post PL, Tyska MJ, O'Connell CB, et al. (2002). "Myosin-IXb is a single-headed and processive motor.". J. Biol. Chem. 277 (14): 11679–83. doi:10.1074/jbc.M111173200. PMID 11801597. 
  • Inoue A, Saito J, Ikebe R, Ikebe M (2002). "Myosin IXb is a single-headed minus-end-directed processive motor.". Nat. Cell Biol. 4 (4): 302–6. doi:10.1038/ncb774. PMID 11901422. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Van Belzen MJ, Meijer JW, Sandkuijl LA, et al. (2003). "A major non-HLA locus in celiac disease maps to chromosome 19.". Gastroenterology 125 (4): 1032–41. PMID 14517787. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Saeki N, Tokuo H, Ikebe M (2005). "BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity.". J. Biol. Chem. 280 (11): 10128–34. doi:10.1074/jbc.M413415200. PMID 15644318. 
  • Cheng J, Kapranov P, Drenkow J, et al. (2005). "Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution.". Science 308 (5725): 1149–54. doi:10.1126/science.1108625. PMID 15790807. 
  • Monsuur AJ, de Bakker PI, Alizadeh BZ, et al. (2006). "Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect.". Nat. Genet. 37 (12): 1341–4. doi:10.1038/ng1680. PMID 16282976. 
  • Kambara T, Ikebe M (2006). "A unique ATP hydrolysis mechanism of single-headed processive myosin, myosin IX.". J. Biol. Chem. 281 (8): 4949–57. doi:10.1074/jbc.M509141200. PMID 16338935. 
  • Nishikawa M, Nishikawa S, Inoue A, et al. (2006). "A unique mechanism for the processive movement of single-headed myosin-IX.". Biochem. Biophys. Res. Commun. 343 (4): 1159–64. doi:10.1016/j.bbrc.2006.03.057. PMID 16616011. 
  • Amundsen SS, Monsuur AJ, Wapenaar MC, et al. (2006). "Association analysis of MYO9B gene polymorphisms with celiac disease in a Swedish/Norwegian cohort.". Hum. Immunol. 67 (4-5): 341–5. doi:10.1016/j.humimm.2006.03.020. PMID 16720215. 
  • Giordano M, Marano C, Mellai M, et al. (2007). "A family-based study does not confirm the association of MYO9B with celiac disease in the Italian population.". Genes Immun. 7 (7): 606–8. doi:10.1038/sj.gene.6364331. PMID 16943798. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • van Bodegraven AA, Curley CR, Hunt KA, et al. (2007). "Genetic variation in myosin IXB is associated with ulcerative colitis.". Gastroenterology 131 (6): 1768–74. doi:10.1053/j.gastro.2006.09.011. PMID 17087940. 
  • Núñez C, Márquez A, Varadé J, et al. (2007). "No evidence of association of the MYO9B polymorphisms with celiac disease in the Spanish population.". Tissue Antigens 68 (6): 489–92. doi:10.1111/j.1399-0039.2006.00699.x. PMID 17176439. 
 This article on a gene on chromosome 19 is a stub. You can help Wikipedia by expanding it.

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