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| Methylparaben | |
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| IUPAC name | Methyl 4-hydroxybenzoate |
| Other names | Methyl paraben; Methyl p-hydroxybenzoate; Methyl parahydroxybenzoate; Nipagin; E number E218 |
| Identifiers | |
| CAS number | [99-76-3] |
| PubChem | |
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| Properties | |
| Molecular formula | C8H8O3 |
| Molar mass | 152.15 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references |
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Methylparaben, also methyl paraben, one of the parabens, has formula CH3(C6H4(OH)COO). It is the methyl ester of p-hydroxybenzoic acid.
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Uses
Methylparaben is an antifungal that is widely used as a preservative for food, drugs, and cosmetics. The compound is often found in carpules of local anaesthetic, acting as a bacteriostatic agent and preservative.
Methylparaben (also called Nipigin, Tegosept, and Mycocten) is commonly used as an anti-fungal agent in Drosophila food media. Usage of methylparaben is known to slow Drosophila growth rate in the larval and pupal stages.
Safety
Methylparaben is readily absorbed from the gastrointestinal tract or through the skin.[1] It is hydrolyzed to p-hydroxybenzoic acid and rapidly excreted without accumulation in the body.[1] Acute toxicity studies have shown that methylparaben is practically non-toxic by both oral and parenteral administration.[1] In a population with normal skin, methyl paraben is practically non-irritating and non-sensitizing; however allergic reactions to ingested parabens have been reported.[1]
See also
References
- ^ a b c d Soni MG, Taylor SL, Greenberg NA, Burdock GA (October 2002). "Evaluation of the health aspects of methyl paraben: a review of the published literature". Food Chem. Toxicol. 40 (10): 1335–73. PMID 12387298.
External links
- Methylparaben at Hazardous Substances Data Bank
- Methylparaben at Household Products Database
Wikipedia content modification information:
- This page was last modified on 15 August 2008, at 09:50.
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