This MedLibrary.org supplementary page on Mitochondrial myopathies is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:
Related Sponsors
 |
This article needs additional citations for verification. Please help improve this article by adding reliable references. Unsourced material may be challenged and removed. (February 2008) |
| Mitochondrial myopathy Classification and external resources |
|
 |
|
|---|---|
| Simplified structure of a typical mitochondrion | |
| ICD-10 | G71.3 |
| MeSH | D017240 |
Mitochondrial myopathy are a type of myopathy associated with mitochondrial disease.
Treatment
Although no cure currently exists, there is some hope for a treatment for this whole class of hereditary diseases with the use of an embryotic mitochindrial transplant. [1]
Examples
Examples of Mitochondrial myopathy include:
- Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like syndrome (MELAS)
- varying degrees of cognitive impairment and dementia
- lactic acidosis
- strokes
- transient ischemic attacks
- hearing loss
- dysmotility
- weight loss
- Myoclonic epilepsy and ragged-red fibers (MERRF)
- progressive myoclonic epilepsy
- clumps of diseased mitochondria accumulate in the subsarcolemmal region of the muscle fiber and appear as "ragged-red fibers" when muscle is stained with modified Gomori trichrome stain
- short stature
- Kearns-Sayre syndrome (KSS)
- external ophthalmoplegia
- cardiac conduction defects
- sensory-neural hearing loss
- Progressive external ophthalmoplegia (PEO)
- progressive ophthalmoparesis is the cardinal feature
- symptomatic overlap with many other mitochondrial myopathies
References
- ^ "Three-parent embryo formed in lab" (web). Scientists believe they have made a potential breakthrough in the treatment of serious disease by creating a human embryo with three separate parents.. BBC News (Tuesday, 5 February 2008, 11:13 GMT). Retrieved on 2008-02-08.
|
||||||||||||||||||||||||||||||||||||||||||||
|
||||||||
Wikipedia content modification information:
- This page was last modified on 6 May 2008, at 01:03.
Wikipedia Authorship and Review
Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.
Wikipedia Usage Guidelines
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Mitochondrial myopathies".
The URL for this specific entry is:
All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.