Welcome to the MedLibrary.org Wikipedia Supplement on Monoamine -- Please Click to Return to Front Page

Noradrenaline is a Monoamine neurotransmitter

Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by a two-carbon chain (-CH₂-CH₂-). All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.

Examples

• Catecholamines:
  • Dopamine (DA)
  • Norepinephrine (NE) (noradrenaline, NA)
  • Epinephrine (Epi) (adrenaline)
• Melatonin
• Histamine
• Serotonin (5-HT)
• Thyronamines, a new group of compounds derived from thyroid hormones
• Trace amines:
  • β-Phenylethylamine (PEA, β-PEA)
  • Tyramine
  • Tryptamine
  • Octopamine
  • 3-iodothyronamine

Specific transporter proteins called monoamine transporters exist that transport monoamines in or out of a cell. These are the dopamine transporter (DAT), serotonin transporter (SERT), and the norepinephrine transporter (NET) in the outer cell membrane and the vesicular monoamine transporter (VMAT1 and VMAT2) in the membrane of intracellular vesicles.

Monoamine oxidase is an enzyme that breaks down monoamine neurotransmitters after they have been released into the synapse.

See also

• Monoamine oxidase
• Monoamine transporter
• Neurotransmitter
• Monoamine Hypothesis

External links

• MeSH Biogenic+monoamines

Wikipedia content modification information:

• This page was last modified on 17 July 2008, at 20:51.

Wikipedia Authorship and Review

Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.

Wikipedia Usage Guidelines

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Monoamine".

The URL for this specific entry is:

• http://medlibrary.org/medwiki/Monoamine

All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.