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| Myoglobinuria Classification and external resources |
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| Model of helical domains in myoglobin. | |
| ICD-10 | R82.1 |
| ICD-9 | 791.3 |
| DiseasesDB | 23059 |
| eMedicine | ped/1535 |
| MeSH | D009212 |
Myoglobinuria is the presence of myoglobin in the urine, usually associated with rhabdomyolysis or muscle destruction. Myoglobin is present in muscle cells as a reserve of oxygen.
Causes
Trauma, vascular problems, venoms, certain drugs and other situations can destroy or damage the muscle, releasing myoglobin to the circulation and thus to the kidneys.
Under ideal situations myoglobin will be filtered and excreted with the urine, but if too much myoglobin is released into the circulation or in case of renal problems, it can occlude the renal filtration system leading to acute tubular necrosis and acute renal insufficiency.
Investigations
After centrifuging, the serum of myologinuria is clear, where the serum of hemoglobinuria after centrifuge is pink.citation needed
External links
- Overview at wustl.edu
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Wikipedia content modification information:
- This page was last modified on 13 July 2008, at 05:54.
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