Neuropeptide Y receptor Y1

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Neuropeptide Y receptor Y1
Identifiers
Symbols NPY1R; NPYR
External IDs OMIM: 162641 MGI: 104963 HomoloGene: 700
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 4886 18166
Ensembl ENSG00000164128 ENSMUSG00000036437
Uniprot P25929 Q3V1K5
Refseq NM_000909 (mRNA)
NP_000900 (protein)		 NM_010934 (mRNA)
NP_035064 (protein)
Location Chr 4: 164.46 - 164.47 Mb Chr 8: 69.63 - 69.64 Mb
Pubmed search [1] [2]

Neuropeptide Y receptor Y1, also known as NPY1R, is a human gene.[1]


See also

References

  1. ^ "Entrez Gene: NPY1R neuropeptide Y receptor Y1".

Further reading

  • Wan CP, Lau BH (1997). "Neuropeptide Y receptor subtypes.". Life Sci. 56 (13): 1055–64. PMID 9001438. 
  • Parker E, Van Heek M, Stamford A (2002). "Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status.". Eur. J. Pharmacol. 440 (2-3): 173–87. PMID 12007534. 
  • Bettio A, Beck-Sickinger AG (2002). "Biophysical methods to study ligand-receptor interactions of neuropeptide Y.". Biopolymers 60 (6): 420–37. doi:10.1002/1097-0282(2001)60:6<420::AID-BIP10183>3.0.CO;2-W. PMID 12209475. 
  • Larhammar D, Blomqvist AG, Yee F, et al. (1992). "Cloning and functional expression of a human neuropeptide Y/peptide YY receptor of the Y1 type.". J. Biol. Chem. 267 (16): 10935–8. PMID 1317848. 
  • Herzog H, Hort YJ, Ball HJ, et al. (1992). "Cloned human neuropeptide Y receptor couples to two different second messenger systems.". Proc. Natl. Acad. Sci. U.S.A. 89 (13): 5794–8. PMID 1321422. 
  • Rose PM, Fernandes P, Lynch JS, et al. (1995). "Cloning and functional expression of a cDNA encoding a human type 2 neuropeptide Y receptor.". J. Biol. Chem. 270 (39): 22661–4. PMID 7559383. 
  • Herzog H, Baumgartner M, Vivero C, et al. (1993). "Genomic organization, localization, and allelic differences in the gene for the human neuropeptide Y Y1 receptor.". J. Biol. Chem. 268 (9): 6703–7. PMID 8095935. 
  • Gicquiaux H, Lecat S, Gaire M, et al. (2002). "Rapid internalization and recycling of the human neuropeptide Y Y(1) receptor.". J. Biol. Chem. 277 (8): 6645–55. doi:10.1074/jbc.M107224200. PMID 11741903. 
  • Sheriff S, F Qureshy A, T Chance W, et al. (2002). "Predominant role by CaM kinase in NPY Y(1) receptor signaling: involvement of CREB [corrected].". Peptides 23 (1): 87–96. PMID 11814622. 
  • Cox HM, Tough IR (2002). "Neuropeptide Y, Y1, Y2 and Y4 receptors mediate Y agonist responses in isolated human colon mucosa.". Br. J. Pharmacol. 135 (6): 1505–12. doi:10.1038/sj.bjp.0704604. PMID 11906964. 
  • Uddman R, Möller S, Nilsson T, et al. (2003). "Neuropeptide Y Y1 and neuropeptide Y Y2 receptors in human cardiovascular tissues.". Peptides 23 (5): 927–34. PMID 12084524. 
  • Cantó Soler MV, Gallo JE, Dodds RA, et al. (2002). "Y1 receptor of neuropeptide Y as a glial marker in proliferative vitreoretinopathy and diseased human retina.". Glia 39 (3): 320–4. doi:10.1002/glia.10107. PMID 12203398. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Berglund MM, Schober DA, Statnick MA, et al. (2003). "The use of bioluminescence resonance energy transfer 2 to study neuropeptide Y receptor agonist-induced beta-arrestin 2 interaction.". J. Pharmacol. Exp. Ther. 306 (1): 147–56. doi:10.1124/jpet.103.051227. PMID 12665544. 
  • Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMID 15231747. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Körner M, Waser B, Reubi JC (2005). "High expression of neuropeptide y receptors in tumors of the human adrenal gland and extra-adrenal paraganglia.". Clin. Cancer Res. 10 (24): 8426–33. doi:10.1158/1078-0432.CCR-04-0821. PMID 15623622. 
 This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.
v • d • e
Transmembrane receptor: G protein-coupled receptors
Class A: Rhodopsin like
α1 (A, B, D) • α2 (A, B, C) • β1 • β2 • β3
CysLT (1, 2) • LTB4 (1, 2) • FPRL1 • OXE • Prostaglandin (DP, EP (1, 2, 3, 4), PGF) • Prostacyclin • Thromboxane
B/W (1, 2) • FF (1, 2) • S • Y (1, 2, 4, 5)
GPR (1, 3, 4, 6, 12, 15, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27, 31, 32, 33, 34, 35, 37, 39, 42, 44, 45, 50, 52, 55, 61, 62, 63, 65, 68, 75, 77, 78, 79, 82, 83, 84, 85, 87, 88, 92, 101, 103, 119, 120, 132, 135, 139, 141, 142, 146, 148, 149, 150, 151, 152, 153, 160, 161, 162, 171, 172, 173, 174, 176, 177, 182)
Adenosine (A1, A2a, A2b, A3) • P2Y (1, 2, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14)
(all but 5-HT3) 5-HT1 (A, B, D, E, F) • 5-HT2 (A, B, C) • 5-HT (4, 5A, 6, 7)
Other
Acetylcholine (M1, M2, M3, M4, M5) • Adrenomedullin • Anaphylatoxin (C3a, C5a) • Angiotensin (1, 2) • Apelin • Bile acid • Bombesin (BRS3, GRPR, NMBR) • Bradykinin (B1, B2) • Cannabinoid (CB1, CB2) • Chemokine • Cholecystokinin (A, B) • Dopamine (D1, D2, D3, D4, D5) • EBI2 • Endothelin (A, B) • Estrogen • Formyl peptide (1, L1, L2) • Free fatty acid (1, 2, 3, 4) • FSH • Galanin (1, 2, 3) • Gonadotropin-releasing hormone (1, 2) • Ghrelin • Histamine (H1, H2, H3, H4) • Kisspeptin • Luteinizing hormone/choriogonadotropin • Lysophospholipid (1, 2, 3, 4, 5, 6, 7, 8) • MAS (1, 1L, D, E, F, G, X1, X2, X3, X4) • Melanocortin (1, 2, 3, 4, 5) • MCHR (1, 2) • Melatonin (1A, 1B) • Motilin • Neuromedin (B, U (1, 2)) • Neurotensin (1, 2) • Opioid (Delta, Kappa, Mu, Nociceptin, but not Sigma) • Olfactory • Opsin (3, 4, 5, 1LW, 1MW, 1SW, RGR, RRH) • Orexin (1, 2) • Oxytocin • Oxoglutarate • PAF • Prokineticin (1, 2) • Prolactin-releasing peptide • Protease-activated (1, 2, 3, 4) • Relaxin (1, 2, 3, 4) • Somatostatin (1, 2, 3, 4, 5) • SREB • Succinate • TAAR (1, 2, 3, 5, 6, 8, 9) • Tachykinin (1, 2, 3) • Thyrotropin • Thyrotropin-releasing hormone • Urotensin-II • Vasopressin (1A, 1B, 2)
Class B: Secretin like
GPR (56, 64, 97, 98, 110, 111, 112, 113, 114, 115, 116, 123, 124, 125, 126, 128, 133, 143, 144, 157)
Other
Class C: Metabotropic
glutamate / pheromone
TAS1R (1, 2, 3) • TAS2R (1, 3, 4, 5, 8, 9, 10, 12, 13, 14, 16, 38, 39, 40, 41, 43, 44, 45, 46, 47, 48, 49, 50)
Other
Calcium-sensing receptor • GABA B (1, 2) • Glutamate receptor (Metabotropic glutamate (1, 2, 3, 4, 5, 6, 7, 8)) • GPRC6A • GPR (156, 158, 179) • RAIG (1, 2, 3, 4)
Frizzled / Smoothened
Frizzled (1, 2, 3, 4, 5, 6, 7, 8, 9, 10) • Smoothened

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  • This page was last modified on 8 July 2008, at 12:01.

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