Nexin

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Nexin can be located on this cross-section of an axoneme

Nexin is a protein that prevents microtubules in the outer layer of axonemes from movement with respect to each other. Otherwise vesicular transport proteins such as dynein would dissolve the whole structure.1

Sorting nexin

Sorting nexins are a large group of proteins with the common characteristic of having a PX domain (a phospholipid-binding motif).2

Such nexins are transcribed from the following genes:

References

  1. ^ Walter F., PhD. Boron (2003). Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders, 1300. ISBN 1-4160-2328-3.  Page 26
  2. ^ Worby CA, Dixon JE (2002). "Sorting out the cellular functions of sorting nexins". Nat. Rev. Mol. Cell Biol. 3 (12): 919–31. doi:10.1038/nrm974. PMID 12461558. 

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  • This page was last modified on 1 August 2008, at 13:46.

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