Nifekalant

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Nifekalant
Systematic (IUPAC) name
6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]
amino]ethylamino]-1,

3-dimethylpyrimidine-2,4-dione
Identifiers
CAS number 130636-43-0
ATC code  ?
PubChem 4486
Chemical data
Formula C19H27N5O5 
Mol. mass 405.44 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status

℞ Prescription only
Routes IV

Nifekalant (INN) is a class III antiarrhythmic agent approved in Japan for the treatment of arrhythmias and ventricular tachycardia.[1] It has the brand name Shinbit.

References

  1. ^ Oyabe A, Sano H (February 2002). "[Pharmacological and clinical profile of nifekalant (shinbit injection), a class III antiarrhythmic drug" (in Japanese). Nippon Yakurigaku Zasshi 119 (2): 103–9. PMID 11862758. 
Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.
v • d • e
Antiarrhythmic agents (C01B)
class I
(Na+ channel blockers)
class Ia (Phase 0)
class Ib (Phase 3)
class Ic (Phase 0)
class II
(Phase 4, beta blockers)
class III
(Phase 3, K+ channel blockers)
class IV
(Phase 4, Ca2+ channel blockers)
class V
(other)

Wikipedia content modification information:

  • This page was last modified on 31 July 2008, at 17:47.

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