This MedLibrary.org supplementary page on Ocular manifestation of systemic disease is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:
Related Sponsors
This is a list of systemic diseases with ocular manifestations.
An ocular manifestation of a systemic disease is an eye condition that directly or indirectly results from a disease process another part of the body. There are many diseases known to cause ocular or visual changes. Diabetes, for example, is the leading cause of new cases of blindness in those aged 20-74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or morecitation needed. Other diseases such as acquired immunodeficiency syndrome (AIDS) and hypertension are commonly found to have associated ocular symptoms.
Systemic allergic diseases
Skin and mucous membrane diseases
- Acne rosacea
- Albinism
- Atopic dermatitis
- Behçet's disease
- Cicatricial pemphigoid
- Ehlers-Danlos syndrome
- Epidermolysis bullosa
- Erythema multiforme
- Goltz-Gorlin syndrome
- Ichthyosis
- Incontinentia pigmenti
- Nevus of Ota
- Pemphigus
- Pseudoxanthoma elasticum
- Psoriasis
- Stevens-Johnson syndrome (Erythema multiforme major)
- Vogt-Koyanagi-Harada syndrome
- Xeroderma pigmentosum
Phacomatoses
- Angiomatosis retinae (Von Hippel-Lindau disease) (Retinocerebellar Capillary Hemangiomatosis)
- Ataxia telangiectasia (Louis-Bar syndrome)
- Encephalotrigeminal angiomatosis (Sturge-Weber syndrome) (Encephalofacial Cavernous Hemangiomatosis)
- Neurofibromatosis (von Recklinghausen's disease)
- Tuberous sclerosis (Bourneville's syndrome)
- Wyburn-Mason syndrome (Racemose Hemangiomatosis)
Collagen diseases
- Ankylosing spondylitis
- Dermatomyositis
- Periarteritis nodosa
- Reiter's syndrome
- Rheumatoid arthritis
- Sarcoidosis
- Scleroderma
- Systemic lupus erythematosus
- Temporal arteritis
- Relapsing polychondritis
- Wegener's granulomatosis (50-60% have ophthalmologic manifestations, which can be a presenting feature in a minority of patients. Orbital disease is the most common manifestation, and may result in proptosis, restrictive ophthalmopathy, chronic orbital pain, and in chronic cases, orbital retraction syndrome and intractable socket pain. Wegener's may also cause injury to the optic nerve, ophthalmoplegia, conjunctivitis, keratitis, scleritis, episcleritis, dacrocystitis, nasolacrimnal duct obstruction, dacroadenitis, uveitis, and retinal vasculitis.
Systemic viral infections
- Varicella (chickenpox)
- Rubeola (measles)
- Rubella (German measles)
- Variola (smallpox)
- Vaccinia
- Herpes simplex
- Herpes zoster
- Mumps
- Infectious mononucleosis
- Influenza
- Cytomegalic inclusion disease
- Pharyngoconjunctival fever (adenovirus 3)
- Epidemic keratoconjunctivitis (adenovirus 8)
- Human immunodeficiency virus (Acquired immunodeficiency syndrome)
Systemic bacterial infections
- Gonorrhea (ophthalmia neonatorum)
- Brucellosis
- Diphtheria
- Lyme disease
- Septicemia bacterial metastatic endophthalmitis
- Tularemia
- Leprosy (Hansen's disease)
- Tuberculosis
- Syphilis
Systemic protozoal infections
- Lymphogranuloma venereum (chlamydial)
- Inclusion conjunctivitis (chlamydial)
- Malaria
- Toxoplasmosis
Systemic fungal infections
- Candida albicans
- Histoplasmosis
- Coccidioidomycosis
- Cryptococcus
- Metastatic fungal endophthalmitis
- Actinomyces
- Streptothrix
Systemic cestode and nematode infections
- Cysticercosis (tapeworm)
- Echinococcosis (hydatid cyst)
- Toxocariasis (Toxocara)
- Trichinosis (Trichinella)
- Onchocerciasis
- Loiasis (Loa loa)
Chromosomal disorders and genetic syndromes
- Cri-du chat syndrome
- Schmid-Fraccaro syndrome
- Turner's syndrome
- Ring-D chromosome
- Monosomy-G syndrome
- Trisomy 13 (Patau's syndrome, D-syndrome)
- Trisomy 18 (Edwards' syndrome, E-syndrome)
- Trisomy 21 (Down's syndrome, mongolism)
- Deletion of long arm of chromosome 18
- Deletion of chromosome 18
- Ciliopathic genetic syndromes -- A number of widely-variant genetic disorders with occular phenotypes have been identifed with genotypical ciliopathy.
Hematologic diseases
Cardiovascular diseases
-
- Arteriosclerosis
- Hypertension
- Pre-eclampsia (Toxemia of pregnancy)
- Occlusive vascular disease (sudden)
- Occlusive vascular disease (slow, progressive)
-
- Thrombosis
- Use of hormonal contraception
- Endocarditis
- Myxoma
- Aortic arch syndrome (Takayasu)
- Pre-eclampsia (Toxemia of pregnancy)
- Thromboangiitis obliternas
- Hereditary telangiectasia (Rendu-Osler-Weber syndrome)
Endocrine diseases
- Cushing's disease
- Addison's disease
- Diabetes mellitus
- Hyperparathyroidism
- Hypoparathyroidism
- Hyperthyroidism
- Hypothyroidism
Gastrointestinal and nutritional disorders
- Alcoholism
- Crohn's disease
- Liver disease
- Malnutrition
- Peptic ulcer disease
- Pancreatic disease
- Regional enteritis or ulcerative colitis
- Vitamin A deficiency
- Vitamin B deficiency
- Vitamin C deficiency
- Hypervitaminosis A, B, and D
- Whipple's disease
Metabolic disorders
- Albinism
- Alkaptonuria
- Amyloidosis
- Chediak-Higashi syndrome
- Cystinosis
- Fabry's disease
- Galactosemia
- Gaucher's disease
- Gout
- Hemochromatosis
- Histiocytosis
- Homocystinuria
- Lipidoses
- Marfan's syndrome
- Marchesani's syndrome
- Mucopolysaccharidosis
- Niemann-Pick disease
- Osteogenesis imperfecta
- Wilson's disease
Musculoskeletal disease
- Albright's disease (fibrous dysplasia of bone)
- Apert's disease
- Conradi's syndrome
- Craniofacial syndromes
- Facial deformity syndromes
- Muscular dystrophy disorders
- Myasthenia gravis
- Osteogenesis imperfecta
- Paget's disease
Pulmonary diseases
- Asthma
- Bronchiogenic carcinoma
- Bronchiectasis
- Cystic fibrosis of the pancreas
- Emphysema
- Pneumonias
- Tuberculosis
Renal disease
- Alport's syndrome
- Azotemia (acute and chronic pyelonephritis)
- Lowe's syndrome
- Medullary cystic disease
- Nephrotic syndrome (acute glomerulonephritis, diabetic kidney, system lupus erythematosus)
- Renal transplantation
- Wilms' tumor (nephroblastoma)
Neoplastic diseases with ocular metastases
References
- Pavan-Langston, Deborah (1990). Manual of Ocular Diagnosis and Therapy. Little, Brown and Company.
Wikipedia content modification information:
- This page was last modified on 1 July 2008, at 16:31.
Wikipedia Authorship and Review
Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.
Wikipedia Usage Guidelines
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Ocular manifestation of systemic disease".
The URL for this specific entry is:
All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.