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An ointment is a viscous semisolid preparation used topically on a variety of body surfaces. These include the skin and the mucus membranes of the eye (an eye ointment), vagina, anus, and nose. An ointment may or may not be medicated.
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Description
The vehicle of an ointment is known as ointment base. The choice of a base depends upon the clinical indication for the ointment, and the different types of ointment bases are:
- Hydrocarbon bases. e.g. hard paraffin, soft paraffin.
- Absorption bases. e.g. wool fat, beewax.
- Water soluble bases. e.g. macrogols 200,300,400.
Properties which affect choice of an ointment base are:
- Stability
- Penetrability
- Solvent property
- Irritant effects
- Ease of application and removal
Methods of preparation of ointments
Trituration: In this finely subdivided insoluble medicaments are evenly distributed by grinding with a small amount of the base followed by dilution with gradually increasing amounts of the base.
Fusion: In this method the ingredients are melted together in descending order of their melting points and stirred to ensure homogenity
See also
External links
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Wikipedia content modification information:
- This page was last modified on 4 June 2008, at 14:26.
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