Opiorphin

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Opiorphin is a chemical compound isolated from human saliva. Initial research with mice shows the compound has a painkilling effect of up to six times that of morphine. It works by stopping the normal breakdown of natural pain-killing opioids in the spine, called enkephalins. It is a relatively simple molecule that should be possible to replicate and synthesize in large quantities.[1][2][3][4]

References

  1. ^ Wisner, Anne; Evelyne Dufour, MichaĆ«l Messaoudi, Amine Nejdi, Audrey Marcel, Marie-Noelle Ungeheuer, and Catherine Rougeot (November 13, 2006). "Human Opiorphin, a natural antinociceptive modulator of opioid-dependent pathways". Proceedings of the National Academy of Sciences 103: 17979. doi:10.1073/pnas.0605865103. Retrieved on 2006-11-14. 
  2. ^ Andy Coghlan (November 13, 2006). "Natural-born painkiller found in human saliva", New Scientist. 
  3. ^ "Natural chemical 'beats morphine'", BBC News (November 14,2006). 
  4. ^ Mary Beckman (November 13, 2006). "Prolonging Painkillers", ScienceNOW. 


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  • This page was last modified on 23 April 2008, at 20:45.

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