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| Pangamic acid | |
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| IUPAC name | 6-(2-Dimethylamino-acetoxy)- 2,3,4,5-tetrahydroxy-hexanoic acid |
| Other names | Vitamin B15 |
| Identifiers | |
| CAS number | [20858-86-0] |
| SMILES |
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| Properties | |
| Molecular formula | C10H19NO8 |
| Molar mass | 281.26 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references |
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Pangamic acid is an ester derived from gluconic acid and dimethylglycine.[1] It was first isolated by Ernst T. Krebs from apricot kernels,[2] and has since been identified in some foods such as pulses.[3] Also found in rice bran & apricot kernels.
Pangamic acid is also known as vitamin B15, but it is not widely accepted as a vitamin for it has not been shown to be essential in the human diet, and a deficiency in consumption of pangamic acid is not known to be associated with any disease.[4]
The calcium salt of pangamic acid, calcium pangamate, is used as a mineral supplement. Like thiamine, pangamic acid causes a temporary drop in blood pressure lasting for about 20 minutes.
References
- ^ Recent data on the structure of pangamic acid (vitamin B15). Telegdy Kovats, Laszlo; Berndorfer-Kraszner, Eva; Juhasz, Agnes; Gabor, Tamas. Acta Alimentaria Academiae Scientiarum Hungaricae (1976), 5(3), 281-8.
- ^ KREBS E T Sr; KREBS E T Jr; BEARD H H; MALIN R; HARRIS A T; BARTLETT C L Pangamic acid sodium: a newly isolated crystalline water-soluble factor; a preliminary report. International record of medicine and general practice clinics (1951), 164(1), 18-23.
- ^ Singh, Jagdev; Handa, Mrs. Geeta; Nandi, L. N.; Manavalan, R.; Atal, C. K. D-Gluconodimethylaminoacetic acid from natural sources. Indian Drugs (1983), 20(5), 185-9.
- ^ "Vitamin B15 - Pangamic Acid", Elson M. Haas M.D.
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- This page was last modified on 20 August 2008, at 09:46.
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