Phenylethanolamine N-methyltransferase

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phenylethanolamine N-methyltransferase
Identifiers
Symbol PNMT
Alt. Symbols PENT
Entrez 5409
HUGO 9160
OMIM 171190
RefSeq NM_002686
UniProt P11086
Other data
EC number 2.1.1.28
Locus Chr. 17 q21-q22

Phenylethanolamine N-methyltransferase (PNMT) is an enzyme found in the adrenal medulla that converts Norepinephrine (Noradrenalin) to Epinephrine (Adrenalin).

PNMT is positively influenced by cortisol, which is produced in the adrenal cortex.

PNMT converts the last step in the synthesis of epinephrine
PNMT converts the last step in the synthesis of epinephrine

External links

v • d • e
Transferase: one carbon transferases (EC 2.1)
2.1.1 - Methyltransferases
2.1.2 - Hydroxy methyl-,
Formyl- and Related Transferases
2.1.3 - Carboxy- and Carbamoyl transferases
2.1.4 - Amidino transferases
v • d • e
Metabolism: amino acid metabolism - neurotransmitter enzymes
histidine→histamine
tyrosine→dopamine→epinephrine
glutamate→GABA
tryptophan→serotonin→melatonin
arginine→NO
choline→Acetylcholine
see also intermediates

Wikipedia content modification information:

  • This page was last modified on 4 October 2008, at 08:42.

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