This MedLibrary.org supplementary page on Pinacidil is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:
Related Sponsors
| Pinacidil | |
|---|---|
 |
|
| IUPAC name | 3-cyano-1-(4-pyridyl)-2-(1,2,2-trimethylpropyl)guanidine |
| Identifiers | |
| CAS number | [85371-64-8] |
| PubChem | |
| SMILES |
|
| Properties | |
| Molecular formula | C13H19N5 |
| Molar mass | 245.32346 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references |
|
Pinacidil is a cyanoguanidine drug that opens ATP-sensitive potassium channels producing peripheral vasodilatation of arterioles.[1] It reduces blood pressure and peripheral resistance and produces fluid retention.[2]
References
- ^ Gollasch M, Bychkov R, Ried C, Behrendt F, Scholze S, Luft FC, Haller H (1995). "Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells". J. Pharmacol. Exp. Ther. 275 (2): 681–92. PMID 7473155.
- ^ Reynolds, James Blair; Martindale, William L. (1996). The extra pharmacopoeia, 31st edition, London: Royal Pharmaceutical Society, 2739 pages. ISBN 0-85369-342-0.
External links
 |
This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
Wikipedia content modification information:
- This page was last modified on 19 May 2008, at 15:39.
Wikipedia Authorship and Review
Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.
Wikipedia Usage Guidelines
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Pinacidil".
The URL for this specific entry is:
All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.