Povidone-iodine

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Povidone-iodine
Systematic (IUPAC) name
2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine.
Identifiers
CAS number 25655-41-8
ATC code S01AX18 D08AG02 D09AA09 D11AC06 G01AX11 R02AA15
PubChem  ?
Chemical data
Formula (C6H9NO)n·xI
Mol. mass  ?
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes topical, when formulated

Povidone-iodine (PVPI) is a water-soluble complex of iodine with polyvinylpyrrolidone (PVP), with from 9.0% to 12.0% available iodine, calculated on a dry basis[1].

PVPI can be further formulated into topical antiseptic products as a solution (with surfactants and/or alcohol), aerosol or ointment at concentrations from 7.5% to 10%. These products are sold over-the-counter (OTC) and used in hospitals for cleansing and disinfecting the skin, preparing the skin preoperatively and treating infections susceptible to iodine.

It works through disruption of pathogen cell walls.

Notes and references

  1. ^ United States Pharmacopeia

See also

Pills  This antimicrobial-related article is a stub. You can help Wikipedia by expanding it.
v • d • e
Antiseptics and disinfectants (D08)
Acridine derivatives
Biguanides and amidines
Phenol and derivatives
Nitrofuran derivatives
Iodine products
Quinoline derivatives
Quaternary ammonium compounds
Mercurial products
Silver compounds
Others
v • d • e
Medicated dressings (D09)
v • d • e
Other dermatological preparations (D11)
Medicated shampoos
Cetrimide - Cadmium compounds - Selenium compounds - Povidone-iodine - Sulfur compounds - Xenysalate
Other dermatologicals
v • d • e
Gynecological anti-infectives and antiseptics (G01)
Antibiotics
Arsenic compounds
Quinoline derivatives
Organic acids
Sulfonamides
Imidazole derivatives
Triazole derivatives
Other
v • d • e
Throat preparations (R02)
Antiseptics
Antibiotics
Local anesthetics

Wikipedia content modification information:

  • This page was last modified on 25 March 2008, at 13:57.

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