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In chemistry, prochiral molecules can be converted from achiral to chiral in a single step.[1]
If two identical substituents are attached to an sp3-hybridized atom, the descriptors pro-R and pro-S are used to distinguish between the two. Promoting the pro-R substituent to higher priority than the identical alternative would result in an R chirality center at the original sp3-hybridized atom, and vice versa.
A trigonal planar sp2-hybridized atom can be converted to a chirality center when a substituent is added to the re or si face of the molecule.
See also
External links
References
- ^ John McMurry. Organic Chemistry, 6ed, Brooks/Cole, 301-303.
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- This page was last modified on 6 October 2008, at 17:11.
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