Prostaglandin analogue

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Synthetic prostaglandin analogues are molecules which are manufactured to bind to a prostaglandin receptor.

Wider use of prostaglandin analogues is limited by unwanted side effects and their abortive potential.

Uses

  • Prostaglandin analogues such as misoprostol are used in treatment of duodenal and gastric ulcers. They exert antisecretory and cytoprotective properties and are especially indicated for the elderly on continuous doses of NSAIDs.
  • Prostaglandin analogues can also be used in the management of open-angle glaucoma. They reduce intra-ocular pressure by enhancing uveoscleral outflow and may also have some effect on the trabecular meshwork as well. Latanoprost, travoprost, unoprostone and bimatoprost are examples of prostaglandin analogues used in the management of open-angle glaucoma.

External links

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Drugs for acid related disorders: Drugs for peptic ulcer and GERD/GORD (A02B)
H2 antagonists
Prostaglandins/analogues
Proton pump inhibitors
Other
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Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)
Vitamin K antagonists
Heparin group
Glycoprotein IIb/IIIa inhibitors
Other platelet
aggregation inhibitors
Enzymes
Direct thrombin inhibitors
Other antithrombotics
Non-medicinal
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Ophthalmologicals: antiglaucoma preparations and miotics (S01E)
Sympathomimetics
Parasympathomimetics
Carbonic anhydrase inhibitors
Beta blocking agents
Prostaglandin analogues
Other agents
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Eicosanoids: prostaglandins
Endogenous/series 2
Prostaglandin analogues

Wikipedia content modification information:

  • This page was last modified on 20 December 2007, at 22:07.

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