Proxibarbal

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Proxibarbital
Systematic (IUPAC) name
5-(2-hydroxypropyl)-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
Identifiers
CAS number 2537-29-3
ATC code N05CA22
PubChem 17336
Chemical data
Formula C10H14N2O4 
Mol. mass 226.229 g/mol
Synonyms Proxibarbital, Centralgol, Ipronal, 5-Allyl-5-(β-hydroxypropyl)barbituric acid
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Proxibarbital (Ipronal) is a barbiturate derivative invented in the 1970s. It has sedative, hypnotic and anticonvulsant properties, and was used in the treatment of migraine headaches in a similar manner to butalbital.[1]

References

  1. ^ Sulman FG, Pfeifer Y, Tal E. Migraine therapy by enzyme induction with proxibarbital (German). Therapie die Gegenwart. 1976 Dec;115(12):2088-103.
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Barbiturates (N01AF, N03AA, N05CA)

Allobarbital • Alphenal • Amobarbital • Aprobarbital • Barbexaclone • Barbital • Brallobarbital • Brophebarbital • Bucolome • Butabarbital • Butalbital • Butobarbital • Butallylonal • Crotylbarbital • Cyclobarbital • Cyclopal • Enallylpropymal • Ethallobarbital • Febarbamate • Heptabarbital • Hexethal • Hexobarbital • Mephobarbital • Metharbital • Methohexital • Methylphenobarbital • Narcobarbital • Nealbarbital • Pentobarbital • Phenobarbital • Phetharbital • Prazitone • Probarbital • Propallylonal • Proxibarbal • Proxibarbital • Reposal • Secbutabarbital • Secobarbital • Sigmodal • Spirobarbital • Talbutal • Thialbarbital • Thiamylal • Thiobarbital • Thiobutabarbital • Thiopental • Valofane • Vinbarbital • Vinylbital
v • d • e
Psycholeptics: hypnotics and sedatives (N05C)
GABAA receptor
Alpha-2 adrenergic receptor
Melatonin receptor
Histamine receptor &
Acetylcholine receptor
GABAB receptor / GHB receptor
GHB Type
Other receptors/
ungrouped
Other

Wikipedia content modification information:

  • This page was last modified on 18 October 2007, at 12:26.

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