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Queens Boulevard runs northwest to southeast across more than half the length of the borough, starting at Crescent Street at the Queensboro Bridge entrance in Long Island City and running through the neighborhoods of Sunnyside, Woodside, Elmhurst, Rego Park, Forest Hills, Kew Gardens, and Briarwood before terminating at Jamaica Avenue in Jamaica. At 7.2 miles (11.6 km), it is one of the longest roads in Queens, and it runs through some of Queens' busiest areas. Much of the road is 12 lanes wide, and at its intersection with Yellowstone Boulevard in Forest Hills, it reaches a high point of 16 lanes. Along much of its length, the road includes both six express lanes (three in each direction) and a service road on each side. Drivers must first exit to the service road in order to make right turns or pull over; left turns must be made from the express lanes, but only at select cross-streets.
This street hosts one of the highest numbers of New York City Subway services in the city. At any one time, five services—the E F M R and the 7 <7>—all use significant stretches of the right of way; only Broadway (ten services), Sixth Avenue (seven), and Seventh Avenue (seven) in Manhattan and Fulton Street (eight) and Flatbush Avenue (six) in Brooklyn carry more at any one time. In addition, the Q60 bus travels its entire length.
Queens Boulevard was built in the early 20th century to connect the new Queensboro Bridge to central Queens, thereby offering an easy outlet from Manhattan. It was created by linking and expanding already-existing streets, such as Thompson Avenue and Hoffman Boulevard, stubs of which still exist. It was widened along with the digging of the IND Queens Boulevard Line subway tunnels in the 1920s and 1930s, and in 1941, the city proposed converting it into a freeway, as was done with the Van Wyck Expressway, but with the onset of World War II, the plan was never completed.
The combination of Queens Boulevard's immense width, heavy automobile traffic, and thriving commercial scene made it the most dangerous thoroughfare in New York City and has earned it city-wide notoriety and morbid nicknames such as "The Boulevard of Death" and "The Boulevard of Broken Bones". From 1993 to 2000, 72 pedestrians, were killed trying to cross the street, an average of 10 per year, with countless more injuries. Since 2001, at least partially in response to major news coverage of the dangerous road, the city government has taken measures to cut down on such incidents, including posting large signs proclaiming that "A Pedestrian Was Killed Crossing Here" at intersections where fatal accidents have occurred and installing more road-rule enforcement cameras.
In 2005, there was hope that there had been a permanent reduction in pedestrian fatalities, because in 2004, only one pedestrian was killed crossing Queens Boulevard. However, 2011 marked the first year that no one was killed crossing the street. 
Popular culture references 
- In the HBO original series, Entourage, main character Vince stars in a fictional film named Queens Boulevard in which he is able to identify with the source material as an original resident of New York. To further understand the story frame, it is important to note that in real life the four leading actors portraying Vince, Eric, Johnny, and Turtle all actually grew up in New York.
- In the movie Coming to America, the address of McDowell's restaurant is 8507 Queens Boulevard in Elmhurst, which is currently a Wendy's fast food restaurant.
- Dukes Boulevard in the video game Grand Theft Auto IV is based on Queens Boulevard.
- A short-lived sitcom entitled 13 Queens Boulevard, aired on ABC-TV in 1979.
- On The Mindy Project Morgan says to Dr. Lahiri that if it weren't for her, he'd be "working at the fake Popeye's on Queens Boulevard".
- "Town of Newtown, Queens County. Long Island - Woodside". 1873. Retrieved 2011-04-19. "shows Thompson Ave. on south border of map"
- "Boulevard of death' claims another life". WABC Television. 2009-04-09. Retrieved 2009-04-10.
- "VIOLENT CITY DEATHS HIT HISTORIC LOWS Everything from murders to auto fatalities falls sharply". NY Daily News. 2005-01-02. Retrieved 2009-04-10.
- NYC DOT Installs Countdown Signals on Queens Boulevard, the Latest in a Year of Unprecendented Safety and Mobility Enhancements Boroughwide