SCN7A

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Sodium channel, voltage-gated, type VII, alpha
Identifiers
Symbols SCN7A; SCN6A
External IDs OMIM: 182392 MGI: 102965 HomoloGene: 55706
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 6332 20272
Ensembl ENSG00000136546 ENSMUSG00000034810
Uniprot Q01118 n/a
Refseq NM_002976 (mRNA)
NP_002967 (protein)		 NM_009135 (mRNA)
NP_033161 (protein)
Location Chr 2: 166.97 - 167.05 Mb Chr 2: 66.47 - 66.59 Mb
Pubmed search [1] [2]

Sodium channel, voltage-gated, type VII, alpha, also known as SCN7A, is a human gene.[1]


Contents

See also

References

  1. ^ "Entrez Gene: SCN7A sodium channel, voltage-gated, type VII, alpha".

Further reading

  • Plummer NW, Meisler MH (1999). "Evolution and diversity of mammalian sodium channel genes.". Genomics 57 (2): 323-31. doi:10.1006/geno.1998.5735. PMID 10198179. 
  • Meyers KJ, Mosley TH, Fox E, et al. (2007). "Genetic variations associated with echocardiographic left ventricular traits in hypertensive blacks.". Hypertension 49 (5): 992-9. doi:10.1161/HYPERTENSIONAHA.106.081265. PMID 17339538. 
  • Zhang KX, Zhu DL, He X, et al. (2004). "[Association of single nucleotide polymorphism in human SCN7A gene with essential hypertension in Chinese]". Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20 (6): 463-7. PMID 14669210. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Goldin AL, Barchi RL, Caldwell JH, et al. (2001). "Nomenclature of voltage-gated sodium channels.". Neuron 28 (2): 365-8. PMID 11144347. 
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548. 
  • George AL, Knops JF, Han J, et al. (1994). "Assignment of a human voltage-dependent sodium channel alpha-subunit gene (SCN6A) to 2q21-q23.". Genomics 19 (2): 395-7. PMID 8188276. 
  • Boyle MB, Heslip LA (1995). "Voltage-dependent Na+ channel mRNA expression in pregnant myometrium.". Recept. Channels 2 (3): 249-53. PMID 7874451. 
  • Han JA, Lu CM, Brown GB, Rado TA (1991). "Direct amplification of a single dissected chromosomal segment by polymerase chain reaction: a human brain sodium channel gene is on chromosome 2q22-q23.". Proc. Natl. Acad. Sci. U.S.A. 88 (2): 335-9. PMID 1846440. 
  • George AL, Knittle TJ, Tamkun MM (1992). "Molecular cloning of an atypical voltage-gated sodium channel expressed in human heart and uterus: evidence for a distinct gene family.". Proc. Natl. Acad. Sci. U.S.A. 89 (11): 4893-7. PMID 1317577. 

External links

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v • d • e
Membrane transport protein: ion channels
Ca2+: Calcium channel
L-type/Cavα (1.1, 1.2, 1.3, 1.4) • N-type/Cavα2.2 • P-type/Cavα(2.1) • Q-type/Cavα2.1 • R-type/Cavα2.3 • T-type/Cavα(3.2)
α2δ-subunits (1, 2) • β-subunits (β1, β2, β3, β4) • γ-subunits (γ1, γ2, γ3, γ4)
Other
Na+: Sodium channel
Navα (1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 7A) • Navβ (1, 2, 3, 4)
Other
K+: Potassium channel
Kvα (1-6) (1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.10, 2.1, 2.2, 3.1, 3.2, 3.3, 3.4, 4.1, 4.2, 4.3, 5.1, 6.1, 6.2, 6.3, 6.4)
Kvα (7-12) (7.1, 7.2, 7.3, 7.4, 7.5, 8.1, 8.2, 9.1, 9.2, 9.3, 10.1, 10.2, 11.1/hERG, 11.2, 11.3, 12.1, 12.2, 12.3)
Kvβ (1, 2, 3) • KCNIP (1, 2, 3, 4) • minK/ISK • MiRP (1, 2, 3) • Shaker gene
Kir (1.1, 2.1, 2.2, 2.3, 2.4) • GIRK/Kir (3.1, 3.2, 3.3, 3.4) • Kir (4.1, 4.2, 5.1, 6.1, 6.2, 7.1)
K2P (1, 2, 3, 4, 5, 6, 7, 9, 10, 12, 13, 15, 16, 17, 18)
M+: TRP cation channel
TRPA (1) • TRPC (1, 2, 3, 4, 4AP, 5, 6, 7) • TRPM (1, 2, 3, 4, 5, 6, 7, 8) • TRPML (1, 2, 3) • TRPP (1, 2) • TRPV (1, 2, 3, 4, 5, 6)
Cl-: Chloride channel
CFTR • CLCA (1, 2, 3, 4) • CLCN (1, 2, 3, 4, 5, 6, 7, KA, KB) • CLIC (1, 2, 3, 4, 5, 6) • CLNS (1A, 1B)
Cyclic nucleotide-gated
α1, α2, α3, α4, β1, β3, H1, H2, H3, H4
Porin
Other/general

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  • This page was last modified on 8 July 2008, at 21:32.

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