SERPINB7

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Serpin peptidase inhibitor, clade B (ovalbumin), member 7
Identifiers
Symbols SERPINB7; DKFZp686D06190; MEGSIN; MGC120014; MGC120015
External IDs OMIM: 603357 MGI: 2151053 HomoloGene: 68363
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 8710 116872
Ensembl ENSG00000166396 ENSMUSG00000067001
Uniprot O75635 Q6P3F8
Refseq NM_001040147 (mRNA)
NP_001035237 (protein)		 NM_027548 (mRNA)
NP_081824 (protein)
Location Chr 18: 59.57 - 59.62 Mb Chr 1: 109.25 - 109.28 Mb
Pubmed search [1] [2]

Serpin peptidase inhibitor, clade B (ovalbumin), member 7, also known as SERPINB7, is a human gene.[1]


See also

References

  1. ^ "Entrez Gene: SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7".

Further reading

  • Tsujimoto M, Tsuruoka N, Ishida N, et al. (1997). "Purification, cDNA cloning, and characterization of a new serpin with megakaryocyte maturation activity.". J. Biol. Chem. 272 (24): 15373–80. PMID 9182567. 
  • Miyata T, Nangaku M, Suzuki D, et al. (1998). "A mesangium-predominant gene, megsin, is a new serpin upregulated in IgA nephropathy.". J. Clin. Invest. 102 (4): 828–36. PMID 9710452. 
  • Inagi R, Miyata T, Suzuki D, et al. (2001). "Specific tissue distribution of megsin, a novel serpin, in the glomerulus and its up-regulation in IgA nephropathy.". Biochem. Biophys. Res. Commun. 286 (5): 1098–106. doi:10.1006/bbrc.2001.5509. PMID 11527413. 
  • Inagi R, Miyata T, Imasawa T, et al. (2003). "Mesangial cell-predominant gene, megsin.". Nephrol. Dial. Transplant. 17 Suppl 9: 32–3. PMID 12386281. 
  • Inagi R, Miyata T, Nangaku M, et al. (2003). "Transcriptional regulation of a mesangium-predominant gene, megsin.". J. Am. Soc. Nephrol. 13 (11): 2715–22. PMID 12397041. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Li YJ, Du Y, Li CX, et al. (2004). "Family-based association study showing that immunoglobulin A nephropathy is associated with the polymorphisms 2093C and 2180T in the 3' untranslated region of the Megsin gene.". J. Am. Soc. Nephrol. 15 (7): 1739–43. PMID 15213261. 
  • Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMID 15342556. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Inagi R, Nangaku M, Usuda N, et al. (2005). "Novel serpinopathy in rat kidney and pancreas induced by overexpression of megsin.". J. Am. Soc. Nephrol. 16 (5): 1339–49. doi:10.1681/ASN.2004070600. PMID 15788472. 
  • Xia Y, Li Y, Du Y, et al. (2006). "Association of MEGSIN 2093C-2180T haplotype at the 3' untranslated region with disease severity and progression of IgA nephropathy.". Nephrol. Dial. Transplant. 21 (6): 1570–4. doi:10.1093/ndt/gfk096. PMID 16431886. 
  • Xia YF, Huang S, Li X, et al. (2006). "A family-based association study of megsin A23167G polymorphism with susceptibility and progression of IgA nephropathy in a Chinese population.". Clin. Nephrol. 65 (3): 153–9. PMID 16550745. 

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v • d • e
Serpins
inhibitory
Cross class inhibitory
MENT · SCCA-1 · crmA
noninhibitory

Wikipedia content modification information:

  • This page was last modified on 10 July 2008, at 10:20.

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