SERPINE2

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Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
Identifiers
Symbols SERPINE2; GDN; PI7; PN1; PNI
External IDs OMIM: 177010 MGI: 101780 HomoloGene: 21247
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 5270 20720
Ensembl ENSG00000135919 ENSMUSG00000026249
Uniprot P07093 Q3TWH7
Refseq NM_006216 (mRNA)
NP_006207 (protein)		 NM_009255 (mRNA)
NP_033281 (protein)
Location Chr 2: 224.55 - 224.61 Mb Chr 1: 79.67 - 79.74 Mb
Pubmed search [1] [2]

Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2, also known as SERPINE2, is a human gene.[1]


Contents

See also

References

  1. ^ "Entrez Gene: SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2".

Further reading

  • Naldini L, Tamagnone L, Vigna E, et al. (1993). "Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor.". EMBO J. 11 (13): 4825–33. PMID 1334458. 
  • Gloor S, Odink K, Guenther J, et al. (1987). "A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins.". Cell 47 (5): 687–93. PMID 2877744. 
  • Sommer J, Gloor SM, Rovelli GF, et al. (1988). "cDNA sequence coding for a rat glia-derived nexin and its homology to members of the serpin superfamily.". Biochemistry 26 (20): 6407–10. PMID 3427015. 
  • Scott RW, Bergman BL, Bajpai A, et al. (1985). "Protease nexin. Properties and a modified purification procedure.". J. Biol. Chem. 260 (11): 7029–34. PMID 3997857. 
  • Carter RE, Cerosaletti KM, Burkin DJ, et al. (1995). "The gene for the serpin thrombin inhibitor (PI7), protease nexin I, is located on human chromosome 2q33-q35 and on syntenic regions in the mouse and sheep genomes.". Genomics 27 (1): 196–9. PMID 7665170. 
  • Magnaldo T, Bernerd F, Darmon M (1995). "Galectin-7, a human 14-kDa S-lectin, specifically expressed in keratinocytes and sensitive to retinoic acid.". Dev. Biol. 168 (2): 259–71. doi:10.1006/dbio.1995.1078. PMID 7729568. 
  • Donovan FM, Vaughan PJ, Cunningham DD (1994). "Regulation of protease nexin-1 target protease specificity by collagen type IV.". J. Biol. Chem. 269 (25): 17199–205. PMID 8006028. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Nykjaer A, Conese M, Christensen EI, et al. (1997). "Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes.". EMBO J. 16 (10): 2610–20. doi:10.1093/emboj/16.10.2610. PMID 9184208. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Li Y, Lu YY (2002). "Applying a highly specific and reproducible cDNA RDA method to clone garlic up-regulated genes in human gastric cancer cells.". World J. Gastroenterol. 8 (2): 213–6. PMID 11925594. 
  • Grabham PW, Monard D, Gallimore PH, Grand RJ. "Modulation of Human Neurite Outgrowth by Serine Proteases: A Comparison of the Interaction of Thrombin and Prothrombin with Glia-Derived Nexin." 3 (7): 663–668. PMID 12106474. 
  • Crisp RJ, Knauer MF, Knauer DJ (2003). "Protease nexin 1 is a potent urinary plasminogen activator inhibitor in the presence of collagen type IV.". J. Biol. Chem. 277 (49): 47285–91. doi:10.1074/jbc.M204813200. PMID 12356769. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Petrovic D, Milanez T, Kobal J, et al. (2003). "Prothrombotic gene polymorphisms and atherothrombotic cerebral infarction.". Acta Neurol. Scand. 108 (2): 109–13. PMID 12859287. 
  • Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMID 15340161. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Kim JA, Tran ND, Li Z, et al. (2006). "Brain endothelial hemostasis regulation by pericytes.". J. Cereb. Blood Flow Metab. 26 (2): 209–17. doi:10.1038/sj.jcbfm.9600181. PMID 16015279. 
  • Navaneetham D, Jin L, Pandey P, et al. (2006). "Structural and mutational analyses of the molecular interactions between the catalytic domain of factor XIa and the Kunitz protease inhibitor domain of protease nexin 2.". J. Biol. Chem. 280 (43): 36165–75. doi:10.1074/jbc.M504990200. PMID 16085935. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

External links

 This article on a gene on chromosome 2 is a stub. You can help Wikipedia by expanding it.
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Serpins
inhibitory
Cross class inhibitory
MENT · SCCA-1 · crmA
noninhibitory

Wikipedia content modification information:

  • This page was last modified on 9 July 2008, at 14:04.

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