This MedLibrary.org supplementary page on Silver sulfadiazine is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:
Related Sponsors
| Silver sulfadiazine | |
|---|---|
 |
|
| Other names | (4-amino-N-2-pyrimidinylbenzenesulfonamidato-NN,01)-silver, sulfadiazine silver, silver (I) sulfadiazine, 4-amino-N-(2-pyrimidinyl)benzenesulfonamide silver salt, dermazine, geben, silvadene |
| Identifiers | |
| CAS number | [22199-08-2] |
| PubChem | |
| Properties | |
| Molecular formula | C10H9AgN4O2S |
| Molar mass | 357.14 g/mol |
| Appearance | Solid |
| Melting point |
285 °C |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references |
|
Silver sulfadiazine is a sulfa derivative topical antibacterial used primarily as a topical burn cream on second- and third-degree burns. The cream is kept applied to the burned skin at all times, for the duration of the healing period or until a graft is applied. It prevents the growth of a wide array of bacteria, as well as yeast, on the damaged skin. Silver sulfadiazine is typically delivered in a 1% solution suspended in a water-soluble base. The chemical itself is poorly soluble, and has only very limited penetration through the skin. Only when applied to very large area burns is absorption into the body generally a problem.
It is also helpful on other shallow, large-area wounds such as abrasions.
Well-known proprietary brand names are Silvadene and Flamazine. The medication is also marketed under Kendall as Thermazene, with the aforementioned silvadene still functioning as a genericized trademark.
Possible side effects
- Areas of dead skin
- Burning sensation
- Red and raised rash on the body
- Argyria (Skin discoloration)
See also
 |
This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
|
|||||||||||||||||||||
Wikipedia content modification information:
- This page was last modified on 31 August 2008, at 20:41.
Wikipedia Authorship and Review
Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.
Wikipedia Usage Guidelines
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Silver sulfadiazine".
The URL for this specific entry is:
All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.