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Sodium picosulfate
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| Systematic (IUPAC) name | |
| disodium 2-[bis(4-sulfonatooxyphenyl)methyl]pyridine | |
| Identifiers | |
| CAS number | |
| ATC code | A06 A06AB58 |
| PubChem | |
| Chemical data | |
| Formula | C18H13NNa2O8S2 |
| Mol. mass | 481.409 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Oral |
Sodium picosulfate (INN, also known as sodium picosulphate) is a contact laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery. It is sold under the trade names Dulcolax, Laxoberal, Picolax, Guttalax and several others.
Side effects
The most common side effects of picosulfate are abdominal cramps and diarrhea.
The use of sodium picosulfate has also been associated with certain electrolyte disturbances, such as hyponatremia and hypokalemia.[1]
References
- ^ ADRAC (February 2002). "Electrolyte disturbances with sodium picosulfate bowel cleansing products". Aust Adv Drug React Bull 21 (1). Free full text from the Australian Therapeutic Goods Administration
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Wikipedia content modification information:
- This page was last modified on 5 August 2007, at 20:10.
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