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Tetrazepam
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| Systematic (IUPAC) name | |
| 7-Chloro-5-(cyclohex-1-enyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one | |
| Identifiers | |
| CAS number | |
| ATC code | M03 |
| PubChem | |
| Chemical data | |
| Formula | C16H17ClN2O |
| Mol. mass | 288.772 |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | 15 hours |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Oral |
Tetrazepam, (Clinoxan, Epsipam, Myolastan, Musaril, Relaxam, Spasmorelax) is a benzodiazepine derivative with anxiolytic and muscle relaxant properties. It is used mainly in Austria, France, Belgium, Germany and Spain to treat muscle spasm, anxiety disorders such as panic attacks, or more rarely to treat depression, premenstrual syndrome or agoraphobia. Tetrazepam has relatively little sedative effect at low doses while still producing useful muscle relaxation and anxiety relief.
The indicated adult dose for muscle spasm is 50 mg three to four times per day, increased if necessary to a maximum of 800mg per day, in divided doses. Tetrazepam is not generally recommended for use in children, except on the advice of a specialist.
Tetrazepam is only available in one strength and formulation, 50mg tablets. This dose is approximately equivalent to 5-7.5mg oral diazepam. Prolonged use, as with all benzodiazepines, should be avoided, as tolerance occurs and there is a risk of possible dependence and a benzodiazepine withdrawal syndrome after stopping or reducing dosage.
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Wikipedia content modification information:
- This page was last modified on 19 July 2008, at 09:08.
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