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Thioxanthene is a molecule in which the oxygen atom in xanthene is replaced with a sulfur atom. Various thioxanthene derivatives are used in the treatment of schizophrenia and psychosis. The activity of these compounds is related to their ability to inhibition transmission at D2 receptors, in the brain.
Thioxanthene derivatives include:
The thioxanthene class of neuroleptic antipsychotic psychotropics is closely related to the phenothiazines, with the nitrogen at position 10 in the phenothiazines, (opposite the sulfur atom in the middle ring), replaced by a carbon atom with a double bond to the side chain. [1]
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- This page was last modified on 18 June 2008, at 19:33.
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