Tromantadine

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Tromantadine
Systematic (IUPAC) name
N-1-adamantyl-N-[2-(dimethylamino)ethoxy]acetamide
Identifiers
CAS number 53783-83-8
ATC code D06BB02
PubChem 64377
Chemical data
Formula C16H28N2O2 
Mol. mass 280.406 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes Topical

Tromantadine is an antiviral medicine used to treat herpes simplex virus. It is available in a topical gel under trade name Viru-Merz. Its performance is similar to aciclovir.

Tromantadine inhibits the early and late events in the virus replication cycle. It changes the glycoproteins of the host cells, therefore impeding the absorption of the virus. It inhibits penetration of the virus. It also prevents uncoating of the virions.

Like rimantadine and amantadine, tromantadine is a derivative of adamantane.

External links

Pills  This antimicrobial-related article is a stub. You can help Wikipedia by expanding it.
v • d • e
Antibiotics and chemotherapeutics for dermatological use (D06)
Antibiotics
Tetracycline and derivatives
Others
Chemotherapeutics
Other
v • d • e
Antivirals, other than for HIV (primarily J05, also S01AD and D06BB)
Anti-herpesvirus (DNA, I)
HPV/MC (DNA, I)
Hepatitis B (DNA, VII)
Hepatitis C (RNA, IV)
Picornavirus (RNA, IV)
Anti-influenza agents (RNA, V)
HIV (Reverse, VI)
Other antiviral agents
general (Inosine, Interferon)
†Undergoing clinical trials, not FDA approved.

Wikipedia content modification information:

  • This page was last modified on 2 August 2007, at 01:48.

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