Uridine

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The chemical structure of uridine
The chemical structure of uridine

Uridine is a molecule (known as a nucleoside) that is formed when uracil is attached to a ribose ring (also known as a ribofuranose) via a β-N1-glycosidic bond.

If uracil is attached to a deoxyribose ring, it is known as a deoxyuridine.

Harvard researchers report that supplementation in rats with a combination of uridine and EPA/DHA omega-3 fatty acids has antidepressant activity equivalent to that of commonly prescribed antidepressant medications, such as Prozac and other SSRIs. [1]

Sugarcane extract is rich in nucleosides, especially uridine.[2] Tomatoes also (about 500-1000 mg. of uridine per kilogram of dry matter).[3]

. Brewer's yeast also contains a good amount of uridine, as yeast is high in RNA, which after digestion is broken down into uridine monophosphate. About 3 percent of yeast (dry weight) results in digestion uridine products. Alternatively, drinking beer also results in increased plasma uridine [4]. About one liter of beer intake results in increased plasma uridine at a level that is comparable to those reached after ingestion of CDP-choline (citicoline) (as in [5]).

References

  1. ^ http://cat.inist.fr/?aModele=afficheN&cpsidt=16548265
  2. ^ http://www.thebody.com/content/art30244.html
  3. ^ http://www.aseanfood.info/Articles/11018411.pdf
  4. ^ http://cat.inist.fr/?aModele=afficheN&cpsidt=13973855
  5. ^ http://www.ncbi.nlm.nih.gov/pubmed/10974208


v • d • e
Nucleobases, nucleosides, and nucleotides
Nucleobases
Nucleosides/
(NB+pentose)
Nucleotides/
(NS+phosphate)
monophosphates (AMP, GMP, UMP, CMP) | diphosphates (ADP, GDP, UDP, CDP) | triphosphates (ATP, GTP, UTP, CTP)
monophosphates (dAMP, dGMP, dUMP, TMP, dCMP) | diphosphates (dADP, dGDP, TDP, dCDP) | triphosphates (dATP, dGTP, TTP, dCTP)
Major families of biochemicals
Saccharides | Carbohydrates | Glycosides | | Amino acids | Peptides | Proteins | Glycoproteins | | Lipids | Terpenes | Steroids | Carotenoids
Alkaloids | Nucleobases | Nucleic acids | | Enzyme cofactors | Flavonoids | Polyketides | Tetrapyrroles
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Wikipedia content modification information:

  • This page was last modified on 8 October 2008, at 08:56.

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