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XX male syndrome (also called de la Chapelle syndrome) is a rare sex chromosomal disorder. Usually it is caused by unequal crossing over between X and Y chromosomes during meiosis. Symptoms include small testes, gynecomastia and sterility. Many individuals with this condition also have effeminate characteristics.
Men typically have one X chromosome and one Y chromosome in each diploid cell of their bodies. Women typically have two X chromosomes. So-called XX males have two X chromosomes; thus they are genetically female but otherwise appear to be male.
See also
- Swyer syndrome
- X chromosome, for other diseases related to the X chromosome.
References
- de la Chapelle A (1972). "Analytic review: nature and origin of males with XX sex chromosomes". Am J Hum Genet 24 (1): 71–105. PMID 4622299.
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- This page was last modified on 7 October 2008, at 07:52.
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