Amoxicillin (Page 4 of 6)

Neonates and infants aged ≤ 12 weeks (≤ 3 months):

Due to incompletely developed renal function affecting elimination of amoxicillin in this age group, the recommended upper dose of amoxicillin is 30 mg/kg/day divided q12h.

Adults and pediatric patients >3 months:

* Dosing for infections caused by less susceptible organisms should follow the recommendations for severe infections.

† The children’s dosage is intended for individuals whose weight is less than 40 kg. Children weighing 40 kg or more should be dosed according to the adult recommendations.
Infection Severity* Usual Usual Dose
Adult Dose for Children
>3 months
Ear/nose/throat Mild/Moderate 500 mg 25 mg/kg/day
every 12 hours in divided doses
or every 12 hours
250 mg or
every 8 hours 20 mg/kg/day
in divided doses
every 8 hours
Severe 875 mg 45 mg/kg/day
every 12 hours in divided doses
or every 12 hours
500 mg or
every 8 hours 40 mg/kg/day
in divided doses
every 8 hours
Lower respiratory Mild/Moderate 875 mg 45 mg/kg/day
Tract or Severe every 12 hours in divided doses
or every 12 hours
500 mg every or
8 hours 40 mg/kg/day
in divided doses
every 8 hours
Skin/Skin Mild/Moderate 500 mg 25 mg/kg/day
Structure every 12 hours in divided doses
or every 12 hours
250 mg every or
8 hours 20 mg/kg/day
in divided doses
every 8 hours
Severe 875 mg 45 mg/kg/day
every 12 hours in divided doses
or every 12 hours
500 mg every or
8 hours 40 mg/kg/day
in divided doses
every 8 hours
Genitourinary Mild/Moderate 500 mg 25 mg/kg/day
Tract every 12 hours in divided doses
or every 12 hours
250 mg every or
8 hours 20 mg/kg/day
in divided doses
every 8 hours
Severe 875 mg 45 mg/kg/day
every 12 hours in divided doses
or every 12 hours
500 mg or
every 8 hours 40 mg/kg/day
in divided doses
every 8 hours
Gonorrhea 3 grams Prepubertal children:
Acute, as 50 mg/kg amoxicillin combined with
uncomplicated single oral dose 25 mg/kg probenecid as a single dose.
ano-genital and

NOTE: SINCE PROBENECID IS CONTRA-

urethral infections in males and females INDICATED IN CHILDREN UNDER 2 YEARS. DO NOT USE THIS REGIMEN IN THESE CASES.

All patients with gonorrhea should be evaluated for syphilis. (See PRECAUTIONS — Laboratory Tests.)

Larger doses may be required for stubborn or severe infections.

All MedLibrary.org resources are included in as near-original form as possible, meaning that the information from the original provider has been rendered here with only typographical or stylistic modifications and not with any substantive alterations of content, meaning or intent.

This site is provided for educational and informational purposes only, in accordance with our Terms of Use, and is not intended as a substitute for the advice of a medical doctor, nurse, nurse practitioner or other qualified health professional.

Privacy Policy | Copyright © 2019. All Rights Reserved.